Anticonvulsant hypersensitivity syndrome associated with Epstein-Barr virus reactivation

Jae Yong Chang, Soo Chan Kim

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8 Citations (Scopus)


We describe a 59-year-old female with severe anticonvulsant hypersensitivity syndrome (AHS) associated with Epstein-Barr virus (EBV) infection. The causative drug was speculated to be carbamazepine. Recurrent EBV infection was demonstrated by the presence of anti-EBV early antigen IgM antibodies and anti-EBV nuclear antigen IgG antibodies. To our knowledge, only one case of drug hypersensitivity syndrome (DHS) associated with EBV has been reported in the English-language literature. Our case is the second report of EBV-associated DHS, which suggests that EBV infection may contribute to the pathogenesis of AHS in a few patients.

Original languageEnglish
Pages (from-to)317-320
Number of pages4
JournalYonsei medical journal
Issue number2
Publication statusPublished - 2007 Apr 1


All Science Journal Classification (ASJC) codes

  • Medicine(all)

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