Anticonvulsant hypersensitivity syndrome associated with Epstein-Barr virus reactivation

Jae Yong Chang; Soo Chan Kim

doi:10.3349/ymj.2007.48.2.317

Anticonvulsant hypersensitivity syndrome associated with Epstein-Barr virus reactivation

Jae Yong Chang, Soo Chan Kim

Department of Dermatology

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

We describe a 59-year-old female with severe anticonvulsant hypersensitivity syndrome (AHS) associated with Epstein-Barr virus (EBV) infection. The causative drug was speculated to be carbamazepine. Recurrent EBV infection was demonstrated by the presence of anti-EBV early antigen IgM antibodies and anti-EBV nuclear antigen IgG antibodies. To our knowledge, only one case of drug hypersensitivity syndrome (DHS) associated with EBV has been reported in the English-language literature. Our case is the second report of EBV-associated DHS, which suggests that EBV infection may contribute to the pathogenesis of AHS in a few patients.

Original language	English
Pages (from-to)	317-320
Number of pages	4
Journal	Yonsei medical journal
Volume	48
Issue number	2
DOIs	https://doi.org/10.3349/ymj.2007.48.2.317
Publication status	Published - 2007 Apr

All Science Journal Classification (ASJC) codes

Medicine(all)

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10.3349/ymj.2007.48.2.317

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Anticonvulsant hypersensitivity syndrome associated with Epstein-Barr virus reactivation

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