Abstract
Oral administration (200 mg/kg) of Foeniculum vulgare fruit methanolic extract exhibited inhibitory effects against acute and subacute inflammatory diseases and type IV allergic reactions and showed a central analgesic effect. Moreover, it significantly increased the plasma superoxide dismutase (SOD) and catalase activities and the high density lipoprotein-cholesterol level. On the contrary, the malondialdehyde (MDA) (as a measure of lipid peroxidation) level was significantly decreased in F. vulgare fruit methanolic extract group compared to the control group (P<0.05). These results seems to support the use of F. vulgare fruit methanolic extract in relieving inflammation.
Original language | English |
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Pages (from-to) | 557-565 |
Number of pages | 9 |
Journal | Fitoterapia |
Volume | 75 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2004 Sep |
Bibliographical note
Funding Information:The work was supported by the Korea Research Foundation Grant (KRF-2002-037-F00013).
All Science Journal Classification (ASJC) codes
- Pharmacology
- Drug Discovery