Antiinflammatory, analgesic and antioxidant activities of the fruit of Foeniculum vulgare

Eun Mi Choi, Jae Kwan Hwang

Research output: Contribution to journalArticle

181 Citations (Scopus)

Abstract

Oral administration (200 mg/kg) of Foeniculum vulgare fruit methanolic extract exhibited inhibitory effects against acute and subacute inflammatory diseases and type IV allergic reactions and showed a central analgesic effect. Moreover, it significantly increased the plasma superoxide dismutase (SOD) and catalase activities and the high density lipoprotein-cholesterol level. On the contrary, the malondialdehyde (MDA) (as a measure of lipid peroxidation) level was significantly decreased in F. vulgare fruit methanolic extract group compared to the control group (P<0.05). These results seems to support the use of F. vulgare fruit methanolic extract in relieving inflammation.

Original languageEnglish
Pages (from-to)557-565
Number of pages9
JournalFitoterapia
Volume75
Issue number6
DOIs
Publication statusPublished - 2004 Sep 1

Fingerprint

Foeniculum
Analgesics
Fruit
Anti-Inflammatory Agents
Antioxidants
Malondialdehyde
Catalase
HDL Cholesterol
Lipid Peroxidation
Superoxide Dismutase
Oral Administration
Hypersensitivity
Inflammation
Control Groups

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery

Cite this

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abstract = "Oral administration (200 mg/kg) of Foeniculum vulgare fruit methanolic extract exhibited inhibitory effects against acute and subacute inflammatory diseases and type IV allergic reactions and showed a central analgesic effect. Moreover, it significantly increased the plasma superoxide dismutase (SOD) and catalase activities and the high density lipoprotein-cholesterol level. On the contrary, the malondialdehyde (MDA) (as a measure of lipid peroxidation) level was significantly decreased in F. vulgare fruit methanolic extract group compared to the control group (P<0.05). These results seems to support the use of F. vulgare fruit methanolic extract in relieving inflammation.",
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Antiinflammatory, analgesic and antioxidant activities of the fruit of Foeniculum vulgare. / Choi, Eun Mi; Hwang, Jae Kwan.

In: Fitoterapia, Vol. 75, No. 6, 01.09.2004, p. 557-565.

Research output: Contribution to journalArticle

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