Antimicrobial resistance in South Korea: A report from the Korean global antimicrobial resistance surveillance system (Kor-GLASS) for 2017

Changseung Liu, Eun Jeong Yoon, Dokyun Kim, Jong Hee Shin, Jeong Hwan Shin, Kyeong Seob Shin, Young Ah Kim, Young Uh, Hyun Soo Kim, Young Ree Kim, Seok Hoon Jeong

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

At the end of 2015, a global action plan on antimicrobial resistance (AMR) was proposed by the World Health Organization, and the Global AMR Surveillance System (GLASS) was subsequently initiated. The Centers for Disease Control and Prevention of South Korea established a customized AMR surveillance system for South Korea, called Kor-GLASS, in early 2016. A pilot phase of Kor-GLASS was operated from May to December 2016 with six sentinel hospitals, and phase I of Kor-GLASS started in January 2017 with eight sentinel hospitals. Previous surveillance data for overestimated AMR due to duplicate isolation of drug-resistant pathogens were corrected and error-free AMR data were compared with those from other countries. One-half (53.2%, 377/708) of Staphylococcus aureus blood strains exhibited resistance to cefoxitin, indicating methicillin-resistant S. aureus. Resistance to ampicillin in Enterococcus faecalis blood strains was rare (0.6%, 1/175), while the resistance rate to penicillin was 26.3% (46/175). Resistance to vancomycin (34.0%, 98/288) and teicoplanin (18.8%, 98/288) was frequently observed in Enterococcus faecium strains. The resistance rate of Escherichia coli strains to cefotaxime was 32.4% (574/1772), and that of Klebsiella pneumoniae strains was 26.1% (181/693). The resistance rates of Pseudomonas aeruginosa strains to imipenem and meropenem were 19.5% (29/149) and 18.1% (27/149), respectively. And 92.1% (187/203) of Acinetobacter baumannii strains were resistant to both imipenem and meropenem. The high incidence of bacteremia caused by major AMR pathogens among hospitalized patients especially in intensive care units emphasized the importance of hospital infection control and the need to improve the crowded hospitalization system in South Korea. The isolation rate of the Salmonella spp. is decreasing, reflecting the current socio-economic status of South Korea. The proportions of bacterial species in the blood strains were similar to those in other Asian countries with similar lifestyles.

Original languageEnglish
Pages (from-to)845-859
Number of pages15
JournalJournal of Infection and Chemotherapy
Volume25
Issue number11
DOIs
Publication statusPublished - 2019 Nov

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Republic of Korea
meropenem
Imipenem
Vancomycin Resistance
Ampicillin Resistance
Teicoplanin
Cefoxitin
Acinetobacter baumannii
Enterococcus faecium
Cefotaxime
Enterococcus faecalis
Klebsiella pneumoniae
Centers for Disease Control and Prevention (U.S.)
Methicillin-Resistant Staphylococcus aureus
Infection Control
Cross Infection
Bacteremia
Salmonella
Penicillins
Pseudomonas aeruginosa

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Pharmacology (medical)
  • Infectious Diseases

Cite this

Liu, Changseung ; Yoon, Eun Jeong ; Kim, Dokyun ; Shin, Jong Hee ; Shin, Jeong Hwan ; Shin, Kyeong Seob ; Kim, Young Ah ; Uh, Young ; Kim, Hyun Soo ; Kim, Young Ree ; Jeong, Seok Hoon. / Antimicrobial resistance in South Korea : A report from the Korean global antimicrobial resistance surveillance system (Kor-GLASS) for 2017. In: Journal of Infection and Chemotherapy. 2019 ; Vol. 25, No. 11. pp. 845-859.
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abstract = "At the end of 2015, a global action plan on antimicrobial resistance (AMR) was proposed by the World Health Organization, and the Global AMR Surveillance System (GLASS) was subsequently initiated. The Centers for Disease Control and Prevention of South Korea established a customized AMR surveillance system for South Korea, called Kor-GLASS, in early 2016. A pilot phase of Kor-GLASS was operated from May to December 2016 with six sentinel hospitals, and phase I of Kor-GLASS started in January 2017 with eight sentinel hospitals. Previous surveillance data for overestimated AMR due to duplicate isolation of drug-resistant pathogens were corrected and error-free AMR data were compared with those from other countries. One-half (53.2{\%}, 377/708) of Staphylococcus aureus blood strains exhibited resistance to cefoxitin, indicating methicillin-resistant S. aureus. Resistance to ampicillin in Enterococcus faecalis blood strains was rare (0.6{\%}, 1/175), while the resistance rate to penicillin was 26.3{\%} (46/175). Resistance to vancomycin (34.0{\%}, 98/288) and teicoplanin (18.8{\%}, 98/288) was frequently observed in Enterococcus faecium strains. The resistance rate of Escherichia coli strains to cefotaxime was 32.4{\%} (574/1772), and that of Klebsiella pneumoniae strains was 26.1{\%} (181/693). The resistance rates of Pseudomonas aeruginosa strains to imipenem and meropenem were 19.5{\%} (29/149) and 18.1{\%} (27/149), respectively. And 92.1{\%} (187/203) of Acinetobacter baumannii strains were resistant to both imipenem and meropenem. The high incidence of bacteremia caused by major AMR pathogens among hospitalized patients especially in intensive care units emphasized the importance of hospital infection control and the need to improve the crowded hospitalization system in South Korea. The isolation rate of the Salmonella spp. is decreasing, reflecting the current socio-economic status of South Korea. The proportions of bacterial species in the blood strains were similar to those in other Asian countries with similar lifestyles.",
author = "Changseung Liu and Yoon, {Eun Jeong} and Dokyun Kim and Shin, {Jong Hee} and Shin, {Jeong Hwan} and Shin, {Kyeong Seob} and Kim, {Young Ah} and Young Uh and Kim, {Hyun Soo} and Kim, {Young Ree} and Jeong, {Seok Hoon}",
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Antimicrobial resistance in South Korea : A report from the Korean global antimicrobial resistance surveillance system (Kor-GLASS) for 2017. / Liu, Changseung; Yoon, Eun Jeong; Kim, Dokyun; Shin, Jong Hee; Shin, Jeong Hwan; Shin, Kyeong Seob; Kim, Young Ah; Uh, Young; Kim, Hyun Soo; Kim, Young Ree; Jeong, Seok Hoon.

In: Journal of Infection and Chemotherapy, Vol. 25, No. 11, 11.2019, p. 845-859.

Research output: Contribution to journalReview article

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T1 - Antimicrobial resistance in South Korea

T2 - A report from the Korean global antimicrobial resistance surveillance system (Kor-GLASS) for 2017

AU - Liu, Changseung

AU - Yoon, Eun Jeong

AU - Kim, Dokyun

AU - Shin, Jong Hee

AU - Shin, Jeong Hwan

AU - Shin, Kyeong Seob

AU - Kim, Young Ah

AU - Uh, Young

AU - Kim, Hyun Soo

AU - Kim, Young Ree

AU - Jeong, Seok Hoon

PY - 2019/11

Y1 - 2019/11

N2 - At the end of 2015, a global action plan on antimicrobial resistance (AMR) was proposed by the World Health Organization, and the Global AMR Surveillance System (GLASS) was subsequently initiated. The Centers for Disease Control and Prevention of South Korea established a customized AMR surveillance system for South Korea, called Kor-GLASS, in early 2016. A pilot phase of Kor-GLASS was operated from May to December 2016 with six sentinel hospitals, and phase I of Kor-GLASS started in January 2017 with eight sentinel hospitals. Previous surveillance data for overestimated AMR due to duplicate isolation of drug-resistant pathogens were corrected and error-free AMR data were compared with those from other countries. One-half (53.2%, 377/708) of Staphylococcus aureus blood strains exhibited resistance to cefoxitin, indicating methicillin-resistant S. aureus. Resistance to ampicillin in Enterococcus faecalis blood strains was rare (0.6%, 1/175), while the resistance rate to penicillin was 26.3% (46/175). Resistance to vancomycin (34.0%, 98/288) and teicoplanin (18.8%, 98/288) was frequently observed in Enterococcus faecium strains. The resistance rate of Escherichia coli strains to cefotaxime was 32.4% (574/1772), and that of Klebsiella pneumoniae strains was 26.1% (181/693). The resistance rates of Pseudomonas aeruginosa strains to imipenem and meropenem were 19.5% (29/149) and 18.1% (27/149), respectively. And 92.1% (187/203) of Acinetobacter baumannii strains were resistant to both imipenem and meropenem. The high incidence of bacteremia caused by major AMR pathogens among hospitalized patients especially in intensive care units emphasized the importance of hospital infection control and the need to improve the crowded hospitalization system in South Korea. The isolation rate of the Salmonella spp. is decreasing, reflecting the current socio-economic status of South Korea. The proportions of bacterial species in the blood strains were similar to those in other Asian countries with similar lifestyles.

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