Abstract
Erythema induratum of Bazin is a chronic, nodular subcutaneous eruption usually occurring on the lower legs of young women. Erythema induratum of Bazin hasbeen regarded as a tuberculide, a hypersensitivity response to Mycobacterium tuberculosis. The pathogenesis of erythema induratum of Bazin associated with tuberculosis is still debatable because mycobacteria cannot be cultured from the skin lesions. QuantiFERON®-TB Gold test detects INF- γ released by T cells in response to Mycobacterium tuberculosis-specific antigens, which offers an improved diagnostic test of latent tuberculosis infection. We experienced two cases of erythema induratum of Bazin, which showed normal chest X-ray and negative TB-PCR. However the QuantiFERON -TB Gold test was positive which led us to a diagnosis of latent tuberculosis infection. Both patients were treated with anti-tuberculosis medications, which was followed by successful resolution of the skin lesions. Therefore, we report the application of the QuantiFERON®-TB Gold test for the confirmation of latent tuberculosis infection in erythema induratum of Bazin patients.
| Original language | English |
|---|---|
| Pages (from-to) | 850-854 |
| Number of pages | 5 |
| Journal | Korean Journal of Dermatology |
| Volume | 47 |
| Issue number | 7 |
| Publication status | Published - 2009 Jul |
All Science Journal Classification (ASJC) codes
- Dermatology
UN SDGs
This output contributes to the following Sustainable Development Goal(s)
