We have successfully synthesized a series of redox-degradable hyperbranched polyglycerols using a disulfide containing monomer, 2-((2-(oxiran-2-ylmethoxy)ethyl)disulfanyl) ethan-1-ol (SSG), to yield PSSG homopolymers and hyperbranched block copolymers, P(G-b-SSG) and P(SSG-b-G), containing nondegradable glycerol (G) monomers. Using these polymers, we have explored the structures of the hyperbranched block copolymers and their related degradation products. Furthermore, side reaction such as reduction of disulfide bond during the polymerization was investigated by employing the free thiol titration experiments. We elucidated the structures of the degradation products with respect to the architecture of the hyperbranched block copolymer under redox conditions using 1H NMR and GPC measurements. For example, the degradation products of P(G-b-SSG) and P(SSG-b-G) are clearly different, demonstrating the clear distinction between linear and hyperbranched block copolymers. We anticipate that this study will extend the structural diversity of PG based polymers and aid the understanding of the structures of degradable hyperbranched PG systems.
|Number of pages||10|
|Journal||Journal of Polymer Science, Part A: Polymer Chemistry|
|Publication status||Published - 2016 Jun 15|
Bibliographical noteFunding Information:
This work was supported by the National Research Foundation of Korea (NRF) grant (No. 2010-0028684) and by the 2014 Research Fund (1.140101.01) of Ulsan National Institute of Science and Technology (UNIST).
All Science Journal Classification (ASJC) codes
- Polymers and Plastics
- Organic Chemistry
- Materials Chemistry