Arterial ageing

Seung Jun Lee, Sung Ha Park

Research output: Contribution to journalReview article

25 Citations (Scopus)

Abstract

Arterial ageing is characterized by age associated degeneration and sclerosis of the media layer of the large arteries. However, besides ageing, clinical conditions, which enhance oxidative stress and inflammation act to accelerate the degree of arterial ageing. In this review, we summarized the pathophysiology and contributing factors that accelerate arterial ageing. Among them, we focused on hypertension, the renin-angiotensin-aldosterone system and vascular inflammation which are modifiable causes of the arterial ageing process. Also, novel treatment targets derived from the disease models such as the Hutchinson Gilford Progeria Syndrome were reviewed.

Original languageEnglish
Pages (from-to)73-79
Number of pages7
JournalKorean Circulation Journal
Volume43
Issue number2
DOIs
Publication statusPublished - 2013 Feb 1

Fingerprint

Progeria
Inflammation
Sclerosis
Renin-Angiotensin System
Blood Vessels
Oxidative Stress
Arteries
Hypertension

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Lee, Seung Jun ; Park, Sung Ha. / Arterial ageing. In: Korean Circulation Journal. 2013 ; Vol. 43, No. 2. pp. 73-79.
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Arterial ageing. / Lee, Seung Jun; Park, Sung Ha.

In: Korean Circulation Journal, Vol. 43, No. 2, 01.02.2013, p. 73-79.

Research output: Contribution to journalReview article

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