A method for detecting artificial DNA using solution-processed In-Ga-Zn-O (IGZO) thin-film transistors (TFTs) was developed. The IGZO TFT had a field-effect mobility ( FET) of 0.07 cm 2/Vs and an on-current (I on) value of about 2.68 A. A dry-wet method was employed to immobilize double-crossover (DX) DNA onto the IGZO surface. After DX DNA immobilization, significant decreases in FET (0.02 cm 2/Vs) and I on (0.247 A) and a positive shift of threshold voltage were observed. These results were attributed to the negatively charged phosphate groups on the DNA backbone, which generated electrostatic interactions in the TFT device.
All Science Journal Classification (ASJC) codes
- Physics and Astronomy (miscellaneous)