Asian-Pacific consensus statement on the management of chronic hepatitis B

A 2005 update

Yun Fan Liaw, Nancy Leung, Richard Guan, George K.K. Lau, Ismail Merican, Geoff McCaughan, Edward Gane, Jia Horng Kao, Masao Omata, B. A. Chutaputti, D. S. Chen, R. N. Chien, G. Cooksley, KwangHyub Han, T. Ichida, M. Y. Lai, L. Lesmana, T. Piratvisuth, S. K. Sarin, J. Sollano & 4 others D. J. Suh, G. B. Yao, C. T. Yeh, O. Yokosuka

Research output: Contribution to journalReview article

307 Citations (Scopus)

Abstract

Background/Aims: A large amount of new data on the treatment of chronic hepatitis B has become available such that the 2003 consensus statement requires revision and update. Methods: New data were presented, discussed and debated in an expert pre-meeting to draft a revision. The revised contents were finalized after discussion in a general meeting of APASL. Results: Conceptual background, including the efficacy and safety profile of currently available and emerging drugs, was reviewed. Nineteen recommendations were formed and unresolved issues and areas for further study were suggested. Conclusion: The current therapy of chronic hepatitis B is modestly effective but not satisfactory. The development of new drugs and new strategies is required to further improve the outcomes of treatment.

Original languageEnglish
Pages (from-to)472-489
Number of pages18
JournalLiver International
Volume25
Issue number3
DOIs
Publication statusPublished - 2005 Jun 1

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Chronic Hepatitis B
Pharmaceutical Preparations
Safety
Therapeutics

All Science Journal Classification (ASJC) codes

  • Hepatology

Cite this

Liaw, Y. F., Leung, N., Guan, R., Lau, G. K. K., Merican, I., McCaughan, G., ... Yokosuka, O. (2005). Asian-Pacific consensus statement on the management of chronic hepatitis B: A 2005 update. Liver International, 25(3), 472-489. https://doi.org/10.1111/j.1478-3231.2005.01134.x
Liaw, Yun Fan ; Leung, Nancy ; Guan, Richard ; Lau, George K.K. ; Merican, Ismail ; McCaughan, Geoff ; Gane, Edward ; Kao, Jia Horng ; Omata, Masao ; Chutaputti, B. A. ; Chen, D. S. ; Chien, R. N. ; Cooksley, G. ; Han, KwangHyub ; Ichida, T. ; Lai, M. Y. ; Lesmana, L. ; Piratvisuth, T. ; Sarin, S. K. ; Sollano, J. ; Suh, D. J. ; Yao, G. B. ; Yeh, C. T. ; Yokosuka, O. / Asian-Pacific consensus statement on the management of chronic hepatitis B : A 2005 update. In: Liver International. 2005 ; Vol. 25, No. 3. pp. 472-489.
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abstract = "Background/Aims: A large amount of new data on the treatment of chronic hepatitis B has become available such that the 2003 consensus statement requires revision and update. Methods: New data were presented, discussed and debated in an expert pre-meeting to draft a revision. The revised contents were finalized after discussion in a general meeting of APASL. Results: Conceptual background, including the efficacy and safety profile of currently available and emerging drugs, was reviewed. Nineteen recommendations were formed and unresolved issues and areas for further study were suggested. Conclusion: The current therapy of chronic hepatitis B is modestly effective but not satisfactory. The development of new drugs and new strategies is required to further improve the outcomes of treatment.",
author = "Liaw, {Yun Fan} and Nancy Leung and Richard Guan and Lau, {George K.K.} and Ismail Merican and Geoff McCaughan and Edward Gane and Kao, {Jia Horng} and Masao Omata and Chutaputti, {B. A.} and Chen, {D. S.} and Chien, {R. N.} and G. Cooksley and KwangHyub Han and T. Ichida and Lai, {M. Y.} and L. Lesmana and T. Piratvisuth and Sarin, {S. K.} and J. Sollano and Suh, {D. J.} and Yao, {G. B.} and Yeh, {C. T.} and O. Yokosuka",
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Liaw, YF, Leung, N, Guan, R, Lau, GKK, Merican, I, McCaughan, G, Gane, E, Kao, JH, Omata, M, Chutaputti, BA, Chen, DS, Chien, RN, Cooksley, G, Han, K, Ichida, T, Lai, MY, Lesmana, L, Piratvisuth, T, Sarin, SK, Sollano, J, Suh, DJ, Yao, GB, Yeh, CT & Yokosuka, O 2005, 'Asian-Pacific consensus statement on the management of chronic hepatitis B: A 2005 update', Liver International, vol. 25, no. 3, pp. 472-489. https://doi.org/10.1111/j.1478-3231.2005.01134.x

Asian-Pacific consensus statement on the management of chronic hepatitis B : A 2005 update. / Liaw, Yun Fan; Leung, Nancy; Guan, Richard; Lau, George K.K.; Merican, Ismail; McCaughan, Geoff; Gane, Edward; Kao, Jia Horng; Omata, Masao; Chutaputti, B. A.; Chen, D. S.; Chien, R. N.; Cooksley, G.; Han, KwangHyub; Ichida, T.; Lai, M. Y.; Lesmana, L.; Piratvisuth, T.; Sarin, S. K.; Sollano, J.; Suh, D. J.; Yao, G. B.; Yeh, C. T.; Yokosuka, O.

In: Liver International, Vol. 25, No. 3, 01.06.2005, p. 472-489.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Asian-Pacific consensus statement on the management of chronic hepatitis B

T2 - A 2005 update

AU - Liaw, Yun Fan

AU - Leung, Nancy

AU - Guan, Richard

AU - Lau, George K.K.

AU - Merican, Ismail

AU - McCaughan, Geoff

AU - Gane, Edward

AU - Kao, Jia Horng

AU - Omata, Masao

AU - Chutaputti, B. A.

AU - Chen, D. S.

AU - Chien, R. N.

AU - Cooksley, G.

AU - Han, KwangHyub

AU - Ichida, T.

AU - Lai, M. Y.

AU - Lesmana, L.

AU - Piratvisuth, T.

AU - Sarin, S. K.

AU - Sollano, J.

AU - Suh, D. J.

AU - Yao, G. B.

AU - Yeh, C. T.

AU - Yokosuka, O.

PY - 2005/6/1

Y1 - 2005/6/1

N2 - Background/Aims: A large amount of new data on the treatment of chronic hepatitis B has become available such that the 2003 consensus statement requires revision and update. Methods: New data were presented, discussed and debated in an expert pre-meeting to draft a revision. The revised contents were finalized after discussion in a general meeting of APASL. Results: Conceptual background, including the efficacy and safety profile of currently available and emerging drugs, was reviewed. Nineteen recommendations were formed and unresolved issues and areas for further study were suggested. Conclusion: The current therapy of chronic hepatitis B is modestly effective but not satisfactory. The development of new drugs and new strategies is required to further improve the outcomes of treatment.

AB - Background/Aims: A large amount of new data on the treatment of chronic hepatitis B has become available such that the 2003 consensus statement requires revision and update. Methods: New data were presented, discussed and debated in an expert pre-meeting to draft a revision. The revised contents were finalized after discussion in a general meeting of APASL. Results: Conceptual background, including the efficacy and safety profile of currently available and emerging drugs, was reviewed. Nineteen recommendations were formed and unresolved issues and areas for further study were suggested. Conclusion: The current therapy of chronic hepatitis B is modestly effective but not satisfactory. The development of new drugs and new strategies is required to further improve the outcomes of treatment.

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U2 - 10.1111/j.1478-3231.2005.01134.x

DO - 10.1111/j.1478-3231.2005.01134.x

M3 - Review article

VL - 25

SP - 472

EP - 489

JO - Liver International

JF - Liver International

SN - 1478-3223

IS - 3

ER -