Aspartate aminotransferase (AST/GOT) and alanine aminotransferase (ALT/GPT) detection techniques

Xing Jiu Huang, Yang Kyu Choi, Hyung Soon Im, Oktay Yarimaga, Euisik Yoon, Hak Sung Kim

Research output: Contribution to journalReview article

111 Citations (Scopus)

Abstract

The levels of aspartate aminotransferase (AST/GOT) and alanine aminotransferase (ALT/GPT) in serum can help people diagnose body tissues especially the heart and the liver are injured or not. This article provides a comprehensive review of research activities that concentrate on AST/GOT and ALT/GPT detection techniques due to their clinical importance. The detection techniques include colorimetric, spectrophotometric, chemiluminescence, chromatography, fluorescence and UV absorbance, radiochemical, and electrochemical techniques. We devote the most attention on experimental principle. In some methods a few representative devices and important conclusions are presented.

Original languageEnglish
Pages (from-to)756-782
Number of pages27
JournalSensors
Volume6
Issue number7
DOIs
Publication statusPublished - 2006 Jan 1

Fingerprint

Electrochemical Techniques
aspartates
Chemiluminescence
alanine
Aspartate Aminotransferases
Chromatography
Luminescence
Alanine Transaminase
Liver
Fluorescence
Tissue
Equipment and Supplies
chemiluminescence
chromatography
Serum
Research
liver
serums
fluorescence

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Atomic and Molecular Physics, and Optics
  • Biochemistry
  • Instrumentation
  • Electrical and Electronic Engineering

Cite this

Huang, Xing Jiu ; Choi, Yang Kyu ; Im, Hyung Soon ; Yarimaga, Oktay ; Yoon, Euisik ; Kim, Hak Sung. / Aspartate aminotransferase (AST/GOT) and alanine aminotransferase (ALT/GPT) detection techniques. In: Sensors. 2006 ; Vol. 6, No. 7. pp. 756-782.
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Aspartate aminotransferase (AST/GOT) and alanine aminotransferase (ALT/GPT) detection techniques. / Huang, Xing Jiu; Choi, Yang Kyu; Im, Hyung Soon; Yarimaga, Oktay; Yoon, Euisik; Kim, Hak Sung.

In: Sensors, Vol. 6, No. 7, 01.01.2006, p. 756-782.

Research output: Contribution to journalReview article

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