Assessment of elastic properties of the descending thoracic aorta by transesophageal echocardiography with acoustic quantification in patients with a stroke

seokmin kang, Jong Won Ha, Namsik Chung, Kil Jin Jang, Mi Seung Shin, Se Joong Rim, Seung Yun Cho

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Previous studies have described the use of transesophageal echocardiography (TEE) with acoustic quantification (AQ) in assessing aortic elastic properties. We hypothesized that patients with a prior history of stroke (ST) may have a higher risk of atherosclerotic change in great vessels compared to nonstroke subjects (NST) and thus have decreased elastic properties. We assessed the elastic properties of the descending thoracic aorta (DTA) by TEE in ST patients and compared them with data in NST patients. Subjects included 31 with ST without any evidence of emboli originating from the heart (age 51 ± 10 years, M:F = 20:11) and 25 age-matched NST (M:F = 8:17). Patients with significant valvular heart disease including aortic and mitral regurgitation, left ventricular dysfunction (ejection fraction < 55%), and congenital heart disease were excluded. Compliance (C), distensibility (D), and stiffness index (SI) were measured using AQ and M-mode measurement at a level of the left atrium. We scored atherosclerotic risk factors (ARF) such as a history of diabetes, hypertension, smoking, hypercholesterolemia, and the presence of atheroma of DTA. There was no evidence of atheroma of DTA in NST. There were no significant differences in heart rate and systolic and diastolic blood pressure between ST and NST patients. Fractional area change (FAC) of DTA was significantly lower in ST than in NST patients (3.2 ± 1.6 vs 5.4 ± 2.5%, P = 0.000). ST patients had significantly lower C (1.2 ± 0.4 vs 1.5 ± 0.7 × 10 -3 cm 2 mmHg -1 , P = 0.039), lower D (0.8 ± 0.3 vs 1.5 ± 0.8 × 10 -3 mmHg -1 , P = 0.000), and higher SI (10.3 ± 8.8 vs 5.3 ± 2.9, P = 0.006) than NST patients. ST patients without atheroma of DTA (n = 21) also had significantly lower C (1.1 ± 0.4 vs 1.5 ± 0.7 × 10 -3 cm 2 mmHg -1 , P = 0.038) and lower D (3.5 ± 1.4 vs 4.8 ± 2.4 × 10 -3 mmHg -1 , P = 0.021) than NST patients. There was a significant positive correlation between SI and the score of ARF (r = 0.51, P = 0.000). The regional elastic properties of DTA measured by TEE with AQ and M-mode method were abnormal in ST. Therefore, TEE with AQ technique may have a possible clinical application for the detection of early atherosclerotic changes such as alteration of elastic properties in morphological normal DTA.

Original languageEnglish
Pages (from-to)713-720
Number of pages8
JournalEchocardiography
Volume17
Issue number8
DOIs
Publication statusPublished - 2000 Jan 1

Fingerprint

Transesophageal Echocardiography
Thoracic Aorta
Acoustics
Stroke
Atherosclerotic Plaques
Blood Pressure
Heart Valve Diseases
Aortic Valve Insufficiency
Mitral Valve Insufficiency
Left Ventricular Dysfunction
Hypercholesterolemia
Embolism
Heart Atria
Stroke Volume
Compliance
Heart Diseases

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

kang, seokmin ; Ha, Jong Won ; Chung, Namsik ; Jang, Kil Jin ; Shin, Mi Seung ; Rim, Se Joong ; Cho, Seung Yun. / Assessment of elastic properties of the descending thoracic aorta by transesophageal echocardiography with acoustic quantification in patients with a stroke. In: Echocardiography. 2000 ; Vol. 17, No. 8. pp. 713-720.
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abstract = "Previous studies have described the use of transesophageal echocardiography (TEE) with acoustic quantification (AQ) in assessing aortic elastic properties. We hypothesized that patients with a prior history of stroke (ST) may have a higher risk of atherosclerotic change in great vessels compared to nonstroke subjects (NST) and thus have decreased elastic properties. We assessed the elastic properties of the descending thoracic aorta (DTA) by TEE in ST patients and compared them with data in NST patients. Subjects included 31 with ST without any evidence of emboli originating from the heart (age 51 ± 10 years, M:F = 20:11) and 25 age-matched NST (M:F = 8:17). Patients with significant valvular heart disease including aortic and mitral regurgitation, left ventricular dysfunction (ejection fraction < 55{\%}), and congenital heart disease were excluded. Compliance (C), distensibility (D), and stiffness index (SI) were measured using AQ and M-mode measurement at a level of the left atrium. We scored atherosclerotic risk factors (ARF) such as a history of diabetes, hypertension, smoking, hypercholesterolemia, and the presence of atheroma of DTA. There was no evidence of atheroma of DTA in NST. There were no significant differences in heart rate and systolic and diastolic blood pressure between ST and NST patients. Fractional area change (FAC) of DTA was significantly lower in ST than in NST patients (3.2 ± 1.6 vs 5.4 ± 2.5{\%}, P = 0.000). ST patients had significantly lower C (1.2 ± 0.4 vs 1.5 ± 0.7 × 10 -3 cm 2 mmHg -1 , P = 0.039), lower D (0.8 ± 0.3 vs 1.5 ± 0.8 × 10 -3 mmHg -1 , P = 0.000), and higher SI (10.3 ± 8.8 vs 5.3 ± 2.9, P = 0.006) than NST patients. ST patients without atheroma of DTA (n = 21) also had significantly lower C (1.1 ± 0.4 vs 1.5 ± 0.7 × 10 -3 cm 2 mmHg -1 , P = 0.038) and lower D (3.5 ± 1.4 vs 4.8 ± 2.4 × 10 -3 mmHg -1 , P = 0.021) than NST patients. There was a significant positive correlation between SI and the score of ARF (r = 0.51, P = 0.000). The regional elastic properties of DTA measured by TEE with AQ and M-mode method were abnormal in ST. Therefore, TEE with AQ technique may have a possible clinical application for the detection of early atherosclerotic changes such as alteration of elastic properties in morphological normal DTA.",
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Assessment of elastic properties of the descending thoracic aorta by transesophageal echocardiography with acoustic quantification in patients with a stroke. / kang, seokmin; Ha, Jong Won; Chung, Namsik; Jang, Kil Jin; Shin, Mi Seung; Rim, Se Joong; Cho, Seung Yun.

In: Echocardiography, Vol. 17, No. 8, 01.01.2000, p. 713-720.

Research output: Contribution to journalArticle

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AU - kang, seokmin

AU - Ha, Jong Won

AU - Chung, Namsik

AU - Jang, Kil Jin

AU - Shin, Mi Seung

AU - Rim, Se Joong

AU - Cho, Seung Yun

PY - 2000/1/1

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N2 - Previous studies have described the use of transesophageal echocardiography (TEE) with acoustic quantification (AQ) in assessing aortic elastic properties. We hypothesized that patients with a prior history of stroke (ST) may have a higher risk of atherosclerotic change in great vessels compared to nonstroke subjects (NST) and thus have decreased elastic properties. We assessed the elastic properties of the descending thoracic aorta (DTA) by TEE in ST patients and compared them with data in NST patients. Subjects included 31 with ST without any evidence of emboli originating from the heart (age 51 ± 10 years, M:F = 20:11) and 25 age-matched NST (M:F = 8:17). Patients with significant valvular heart disease including aortic and mitral regurgitation, left ventricular dysfunction (ejection fraction < 55%), and congenital heart disease were excluded. Compliance (C), distensibility (D), and stiffness index (SI) were measured using AQ and M-mode measurement at a level of the left atrium. We scored atherosclerotic risk factors (ARF) such as a history of diabetes, hypertension, smoking, hypercholesterolemia, and the presence of atheroma of DTA. There was no evidence of atheroma of DTA in NST. There were no significant differences in heart rate and systolic and diastolic blood pressure between ST and NST patients. Fractional area change (FAC) of DTA was significantly lower in ST than in NST patients (3.2 ± 1.6 vs 5.4 ± 2.5%, P = 0.000). ST patients had significantly lower C (1.2 ± 0.4 vs 1.5 ± 0.7 × 10 -3 cm 2 mmHg -1 , P = 0.039), lower D (0.8 ± 0.3 vs 1.5 ± 0.8 × 10 -3 mmHg -1 , P = 0.000), and higher SI (10.3 ± 8.8 vs 5.3 ± 2.9, P = 0.006) than NST patients. ST patients without atheroma of DTA (n = 21) also had significantly lower C (1.1 ± 0.4 vs 1.5 ± 0.7 × 10 -3 cm 2 mmHg -1 , P = 0.038) and lower D (3.5 ± 1.4 vs 4.8 ± 2.4 × 10 -3 mmHg -1 , P = 0.021) than NST patients. There was a significant positive correlation between SI and the score of ARF (r = 0.51, P = 0.000). The regional elastic properties of DTA measured by TEE with AQ and M-mode method were abnormal in ST. Therefore, TEE with AQ technique may have a possible clinical application for the detection of early atherosclerotic changes such as alteration of elastic properties in morphological normal DTA.

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