Assessment of myocardial delayed enhancement with cardiac computed tomography in cardiomyopathies: a prospective comparison with delayed enhancement cardiac magnetic resonance imaging

Hye Jeong Lee, Dong Jin Im, Jong Chan Youn, Suyon Chang, Young Joo Suh, Yoo Jin Hong, Youngjin Kim, Jin Hur, Byoung Wook Choi

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

To evaluate the feasibility of cardiac CT for the evaluation of myocardial delayed enhancement (MDE) in the assessment of patients with cardiomyopathy, compared to cardiac MRI. A total of 37 patients (mean age 54.9 ± 15.7 years, 24 men) who underwent cardiac MRI to evaluate cardiomyopathy were enrolled. Dual-energy ECG-gated cardiac CT was acquired 12 min after contrast injection. Two observers evaluated cardiac MRI and cardiac CT at different kV settings (100, 120 and 140 kV) independently for MDE pattern-classification (patchy, transmural, subendocardial, epicardial and mesocardial), differentiation between ischemic and non-ischemic cardiomyopathy and MDE quantification (percentage MDE). Kappa statics and the intraclass correlation coefficient were used for statistical analysis. Among different kV settings, 100-kV CT showed excellent agreements compared to cardiac MRI for MDE detection (κ = 0.886 and 0.873, respectively), MDE pattern-classification (κ = 0.888 and 0.881, respectively) and differentiation between ischemic and non-ischemic cardiomyopathy (κ = 1.000 and 0.893, respectively) for both Observer 1 and Observer 2. The Bland–Altman plot between MRI and 100-kV CT for the percentage MDE showed a very small bias (−0.15%) with 95% limits of agreement of −7.02 and 6.72. Cardiac CT using 100 kV might be an alternative method to cardiac MRI in the assessment of cardiomyopathy, particularly in patients with contraindications to cardiac MRI.

Original languageEnglish
Pages (from-to)577-584
Number of pages8
JournalInternational Journal of Cardiovascular Imaging
Volume33
Issue number4
DOIs
Publication statusPublished - 2017 Apr 1

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Cardiomyopathies
Tomography
Magnetic Resonance Imaging
Electrocardiography
Injections

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Lee, Hye Jeong ; Im, Dong Jin ; Youn, Jong Chan ; Chang, Suyon ; Suh, Young Joo ; Hong, Yoo Jin ; Kim, Youngjin ; Hur, Jin ; Choi, Byoung Wook. / Assessment of myocardial delayed enhancement with cardiac computed tomography in cardiomyopathies : a prospective comparison with delayed enhancement cardiac magnetic resonance imaging. In: International Journal of Cardiovascular Imaging. 2017 ; Vol. 33, No. 4. pp. 577-584.
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abstract = "To evaluate the feasibility of cardiac CT for the evaluation of myocardial delayed enhancement (MDE) in the assessment of patients with cardiomyopathy, compared to cardiac MRI. A total of 37 patients (mean age 54.9 ± 15.7 years, 24 men) who underwent cardiac MRI to evaluate cardiomyopathy were enrolled. Dual-energy ECG-gated cardiac CT was acquired 12 min after contrast injection. Two observers evaluated cardiac MRI and cardiac CT at different kV settings (100, 120 and 140 kV) independently for MDE pattern-classification (patchy, transmural, subendocardial, epicardial and mesocardial), differentiation between ischemic and non-ischemic cardiomyopathy and MDE quantification (percentage MDE). Kappa statics and the intraclass correlation coefficient were used for statistical analysis. Among different kV settings, 100-kV CT showed excellent agreements compared to cardiac MRI for MDE detection (κ = 0.886 and 0.873, respectively), MDE pattern-classification (κ = 0.888 and 0.881, respectively) and differentiation between ischemic and non-ischemic cardiomyopathy (κ = 1.000 and 0.893, respectively) for both Observer 1 and Observer 2. The Bland–Altman plot between MRI and 100-kV CT for the percentage MDE showed a very small bias (−0.15{\%}) with 95{\%} limits of agreement of −7.02 and 6.72. Cardiac CT using 100 kV might be an alternative method to cardiac MRI in the assessment of cardiomyopathy, particularly in patients with contraindications to cardiac MRI.",
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Assessment of myocardial delayed enhancement with cardiac computed tomography in cardiomyopathies : a prospective comparison with delayed enhancement cardiac magnetic resonance imaging. / Lee, Hye Jeong; Im, Dong Jin; Youn, Jong Chan; Chang, Suyon; Suh, Young Joo; Hong, Yoo Jin; Kim, Youngjin; Hur, Jin; Choi, Byoung Wook.

In: International Journal of Cardiovascular Imaging, Vol. 33, No. 4, 01.04.2017, p. 577-584.

Research output: Contribution to journalArticle

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T2 - a prospective comparison with delayed enhancement cardiac magnetic resonance imaging

AU - Lee, Hye Jeong

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AU - Youn, Jong Chan

AU - Chang, Suyon

AU - Suh, Young Joo

AU - Hong, Yoo Jin

AU - Kim, Youngjin

AU - Hur, Jin

AU - Choi, Byoung Wook

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N2 - To evaluate the feasibility of cardiac CT for the evaluation of myocardial delayed enhancement (MDE) in the assessment of patients with cardiomyopathy, compared to cardiac MRI. A total of 37 patients (mean age 54.9 ± 15.7 years, 24 men) who underwent cardiac MRI to evaluate cardiomyopathy were enrolled. Dual-energy ECG-gated cardiac CT was acquired 12 min after contrast injection. Two observers evaluated cardiac MRI and cardiac CT at different kV settings (100, 120 and 140 kV) independently for MDE pattern-classification (patchy, transmural, subendocardial, epicardial and mesocardial), differentiation between ischemic and non-ischemic cardiomyopathy and MDE quantification (percentage MDE). Kappa statics and the intraclass correlation coefficient were used for statistical analysis. Among different kV settings, 100-kV CT showed excellent agreements compared to cardiac MRI for MDE detection (κ = 0.886 and 0.873, respectively), MDE pattern-classification (κ = 0.888 and 0.881, respectively) and differentiation between ischemic and non-ischemic cardiomyopathy (κ = 1.000 and 0.893, respectively) for both Observer 1 and Observer 2. The Bland–Altman plot between MRI and 100-kV CT for the percentage MDE showed a very small bias (−0.15%) with 95% limits of agreement of −7.02 and 6.72. Cardiac CT using 100 kV might be an alternative method to cardiac MRI in the assessment of cardiomyopathy, particularly in patients with contraindications to cardiac MRI.

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