Association between ambient air pollution and hyperuricemia in traffic police officers in China: a cohort study

Yong Xiang Tang, Michael S. Bloom, Zhengmin Qian, Echu Liu, Daire R. Jansson, Michael G. Vaughn, Hua Liang Lin, Lv Wu Xiao, Chuan Wei Duan, Lie Yang, Xiao Yun Xu, Yan Ru Li, Ling Zhu, Guang Hui Dong, Yi Min Liu

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

To evaluate the association between ambient air pollution and hyperuricemia, we prospectively followed 1748 traffic police officers without hyperuricemia at baseline (2009–2014) from 11 districts in Guangzhou, China. We calculated six-year average PM10, SO2 and NO2 concentrations using data collected from air monitoring stations. The hazard ratios for hyperuricemia per 10 µg/m3 increase in air pollutants were 1.46 (95% CI: 1.28–1.68) for PM10, 1.23 (95% CI: 1.00–1.51) for SO2, and 1.43 (95% CI: 1.26–1.61) for NO2. We also identified changes in the ratio of serum uric acid to serum creatinine concentrations (ua/cre) per 10 µg/m3 increase in air pollutants as 11.54% (95% CI: 8.14%-14.93%) higher for PM10, 5.09% (95% CI: 2.76%-7.42%) higher for SO2, and 5.13% (95% CI: 2.35%-7.92%) higher for NO2, respectively. Long-term exposure to ambient air pollution was associated with a higher incidence of hyperuricemia and an increase in ua/cre among traffic police officers.

Original languageEnglish
Pages (from-to)54-62
Number of pages9
JournalInternational Journal of Environmental Health Research
Volume31
Issue number1
DOIs
Publication statusPublished - 2021

Bibliographical note

Funding Information:
This research was supported by grants from The Key Medical Disciplines and Specialties Program of Guangzhou, and the National Natural Science Foundation of China (81872582).

All Science Journal Classification (ASJC) codes

  • Pollution
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

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