Association between periodontal flap surgery for periodontitis and vasculogenic erectile dysfunction in Koreans

Jae Hong Lee, Jung Kyu Choi, Sang Hyun Kim, Kyung Hyun Cho, Young Taek Kim, Seong Ho Choi, Ui Won Jung

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)


Purpose: The National Health Insurance Service-National Sample Cohort and medical checkup data from 2002 to 2013 were used to evaluate the association between periodontal surgery for the treatment of periodontitis (PSTP) and vasculogenic erectile dysfunction (VED). Methods: Bivariate and multivariate logistic regression analyses were applied to a longitudinal retrospective database to assess the association between PSTP and VED while adjusting for the potential confounding effects of sociodemographic factors (age, household income, insurance status, health status, residence area, and smoking status) and comorbidities (diabetes mellitus, angina pectoris, cerebral infarction, and myocardial infarction). Results: Among the 7,148 PSTP within the 268,296 recruited subjects, the overall prevalence of VED in PSTP was 1.43% (n=102). The bivariate analysis showed that VED was significantly related to PSTP (odds ratio [OR], 1.99; 95% confidence interval [CI], 1.38-2.06; P < 0.001), and this was confirmed in the multivariate analysis after adjusting for sociodemographic factors and comorbidities (OR, 1.29; 95% CI, 1.06-1.58; P=0.002). Conclusions: Subjects with a history of periodontal flap surgery had a significantly higher risk of VED, after adjusting for potential confounding factors. Further studies are required to identify the key mechanisms underlying the association between severe periodontal disease and VED.

Original languageEnglish
Pages (from-to)96-105
Number of pages10
JournalJournal of Periodontal and Implant Science
Issue number2
Publication statusPublished - 2017 Apr 1

Bibliographical note

Publisher Copyright:
© 2017. Korean Academy of Periodontology.

All Science Journal Classification (ASJC) codes

  • Oral Surgery
  • Periodontics


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