Association between resting heart rate and arterial stiffness in Korean adults

Byoung Jin Park, Hye Ree Lee, Jae Yong Shim, Jung Hyun Lee, Dong Hyuk Jung, Yongjae Lee

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Background. - Higher resting heart rate, a simple and useful indicator of autonomic balance and metabolic rate, has emerged as an independent predictor for atherosclerotic cardiovascular disease. Aim. - To determine the association between resting heart rate and arterial stiffness measured by brachial-ankle pulse wave velocity (baPWV). Methods. - We examined the association between resting heart rate and baPWV in 641 Korean adults (366 men, 275 women) in a health examination program. A high baPWV was defined as greater than 1450 cm/s (> 75th percentile). The odds ratios for high baPWVs were calculated using multivariable logistic regression analysis after adjusting for confounding variables across heart rate quartiles (Q1 ≤ 56, Q2 = 57-62, Q3 = 63-68, Q4 ≥ 69 beats/min). Results. - Age-adjusted baPWV mean values increased gradually with heart rate quartile (Q1 = 1281, Q2 = 1285, Q3 = 1354, Q4 = 1416 cm/s). The odds ratios (95% confidence intervals) for high baPWVs in each heart rate quartile were 1.00, 1.28 (0.57-2.86), 2.63 (1.20-5.79) and 3.66 (1.66-8.05), respectively, after adjusting for age, sex, smoking status, alcohol intake, exercise, body mass index, hypertension medication, diabetes medication, hyperlipidaemia medication, mean arterial blood pressure, fasting plasma glucose, total cholesterol, triglycerides, high-density lipoprotein cholesterol, white blood cell count, aspartate aminotransferase, alanine aminotransferase, 7-glutamyltransferase and uric acid. Conclusion. - These findings indicate that a higher resting heart rate is independently associated with arterial stiffness. Accordingly, early detection of increased resting heart rate is important for preservation of arterial function and assessment of cardiovascular risk.

Original languageEnglish
Pages (from-to)246-252
Number of pages7
JournalArchives of Cardiovascular Diseases
Volume103
Issue number4
DOIs
Publication statusPublished - 2010 Jan 1

Fingerprint

Vascular Stiffness
Heart Rate
Pulse Wave Analysis
Ankle
Arm
Arterial Pressure
Odds Ratio
Confounding Factors (Epidemiology)
Aspartate Aminotransferases
Hyperlipidemias
Uric Acid
Alanine Transaminase
Leukocyte Count
HDL Cholesterol
Fasting
Triglycerides
Body Mass Index
Cardiovascular Diseases
Logistic Models
Smoking

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Park, Byoung Jin ; Lee, Hye Ree ; Shim, Jae Yong ; Lee, Jung Hyun ; Jung, Dong Hyuk ; Lee, Yongjae. / Association between resting heart rate and arterial stiffness in Korean adults. In: Archives of Cardiovascular Diseases. 2010 ; Vol. 103, No. 4. pp. 246-252.
@article{2c5d5302941e48f2998f633ff5e8f548,
title = "Association between resting heart rate and arterial stiffness in Korean adults",
abstract = "Background. - Higher resting heart rate, a simple and useful indicator of autonomic balance and metabolic rate, has emerged as an independent predictor for atherosclerotic cardiovascular disease. Aim. - To determine the association between resting heart rate and arterial stiffness measured by brachial-ankle pulse wave velocity (baPWV). Methods. - We examined the association between resting heart rate and baPWV in 641 Korean adults (366 men, 275 women) in a health examination program. A high baPWV was defined as greater than 1450 cm/s (> 75th percentile). The odds ratios for high baPWVs were calculated using multivariable logistic regression analysis after adjusting for confounding variables across heart rate quartiles (Q1 ≤ 56, Q2 = 57-62, Q3 = 63-68, Q4 ≥ 69 beats/min). Results. - Age-adjusted baPWV mean values increased gradually with heart rate quartile (Q1 = 1281, Q2 = 1285, Q3 = 1354, Q4 = 1416 cm/s). The odds ratios (95{\%} confidence intervals) for high baPWVs in each heart rate quartile were 1.00, 1.28 (0.57-2.86), 2.63 (1.20-5.79) and 3.66 (1.66-8.05), respectively, after adjusting for age, sex, smoking status, alcohol intake, exercise, body mass index, hypertension medication, diabetes medication, hyperlipidaemia medication, mean arterial blood pressure, fasting plasma glucose, total cholesterol, triglycerides, high-density lipoprotein cholesterol, white blood cell count, aspartate aminotransferase, alanine aminotransferase, 7-glutamyltransferase and uric acid. Conclusion. - These findings indicate that a higher resting heart rate is independently associated with arterial stiffness. Accordingly, early detection of increased resting heart rate is important for preservation of arterial function and assessment of cardiovascular risk.",
author = "Park, {Byoung Jin} and Lee, {Hye Ree} and Shim, {Jae Yong} and Lee, {Jung Hyun} and Jung, {Dong Hyuk} and Yongjae Lee",
year = "2010",
month = "1",
day = "1",
doi = "10.1016/j.acvd.2010.03.004",
language = "English",
volume = "103",
pages = "246--252",
journal = "Archives of Cardiovascular Diseases",
issn = "1875-2136",
publisher = "Elsevier Masson",
number = "4",

}

Association between resting heart rate and arterial stiffness in Korean adults. / Park, Byoung Jin; Lee, Hye Ree; Shim, Jae Yong; Lee, Jung Hyun; Jung, Dong Hyuk; Lee, Yongjae.

In: Archives of Cardiovascular Diseases, Vol. 103, No. 4, 01.01.2010, p. 246-252.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Association between resting heart rate and arterial stiffness in Korean adults

AU - Park, Byoung Jin

AU - Lee, Hye Ree

AU - Shim, Jae Yong

AU - Lee, Jung Hyun

AU - Jung, Dong Hyuk

AU - Lee, Yongjae

PY - 2010/1/1

Y1 - 2010/1/1

N2 - Background. - Higher resting heart rate, a simple and useful indicator of autonomic balance and metabolic rate, has emerged as an independent predictor for atherosclerotic cardiovascular disease. Aim. - To determine the association between resting heart rate and arterial stiffness measured by brachial-ankle pulse wave velocity (baPWV). Methods. - We examined the association between resting heart rate and baPWV in 641 Korean adults (366 men, 275 women) in a health examination program. A high baPWV was defined as greater than 1450 cm/s (> 75th percentile). The odds ratios for high baPWVs were calculated using multivariable logistic regression analysis after adjusting for confounding variables across heart rate quartiles (Q1 ≤ 56, Q2 = 57-62, Q3 = 63-68, Q4 ≥ 69 beats/min). Results. - Age-adjusted baPWV mean values increased gradually with heart rate quartile (Q1 = 1281, Q2 = 1285, Q3 = 1354, Q4 = 1416 cm/s). The odds ratios (95% confidence intervals) for high baPWVs in each heart rate quartile were 1.00, 1.28 (0.57-2.86), 2.63 (1.20-5.79) and 3.66 (1.66-8.05), respectively, after adjusting for age, sex, smoking status, alcohol intake, exercise, body mass index, hypertension medication, diabetes medication, hyperlipidaemia medication, mean arterial blood pressure, fasting plasma glucose, total cholesterol, triglycerides, high-density lipoprotein cholesterol, white blood cell count, aspartate aminotransferase, alanine aminotransferase, 7-glutamyltransferase and uric acid. Conclusion. - These findings indicate that a higher resting heart rate is independently associated with arterial stiffness. Accordingly, early detection of increased resting heart rate is important for preservation of arterial function and assessment of cardiovascular risk.

AB - Background. - Higher resting heart rate, a simple and useful indicator of autonomic balance and metabolic rate, has emerged as an independent predictor for atherosclerotic cardiovascular disease. Aim. - To determine the association between resting heart rate and arterial stiffness measured by brachial-ankle pulse wave velocity (baPWV). Methods. - We examined the association between resting heart rate and baPWV in 641 Korean adults (366 men, 275 women) in a health examination program. A high baPWV was defined as greater than 1450 cm/s (> 75th percentile). The odds ratios for high baPWVs were calculated using multivariable logistic regression analysis after adjusting for confounding variables across heart rate quartiles (Q1 ≤ 56, Q2 = 57-62, Q3 = 63-68, Q4 ≥ 69 beats/min). Results. - Age-adjusted baPWV mean values increased gradually with heart rate quartile (Q1 = 1281, Q2 = 1285, Q3 = 1354, Q4 = 1416 cm/s). The odds ratios (95% confidence intervals) for high baPWVs in each heart rate quartile were 1.00, 1.28 (0.57-2.86), 2.63 (1.20-5.79) and 3.66 (1.66-8.05), respectively, after adjusting for age, sex, smoking status, alcohol intake, exercise, body mass index, hypertension medication, diabetes medication, hyperlipidaemia medication, mean arterial blood pressure, fasting plasma glucose, total cholesterol, triglycerides, high-density lipoprotein cholesterol, white blood cell count, aspartate aminotransferase, alanine aminotransferase, 7-glutamyltransferase and uric acid. Conclusion. - These findings indicate that a higher resting heart rate is independently associated with arterial stiffness. Accordingly, early detection of increased resting heart rate is important for preservation of arterial function and assessment of cardiovascular risk.

UR - http://www.scopus.com/inward/record.url?scp=77954863651&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77954863651&partnerID=8YFLogxK

U2 - 10.1016/j.acvd.2010.03.004

DO - 10.1016/j.acvd.2010.03.004

M3 - Article

C2 - 20656635

AN - SCOPUS:77954863651

VL - 103

SP - 246

EP - 252

JO - Archives of Cardiovascular Diseases

JF - Archives of Cardiovascular Diseases

SN - 1875-2136

IS - 4

ER -