Association between serum triglyceride to high-density lipoprotein cholesterol ratio and sarcopenia in elderly Korean males: The Korean National Health and Nutrition Examination Survey

Tae Ha Chung, Yu Jin Kwon, Jae Yong Shim, Yong Jae Lee

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Background We investigated the association between the triglycerides to high-density lipoprotein cholesterol (TG/HDL) ratio and sarcopenia in elderly Korean males. Methods We examined the relationship between the TG/HDL ratio and sarcopenia in 879 elderly males ≥ 60 years who participated in the 2010–2011 KNHANES. Sarcopenia was defined as an appendicular skeletal muscle mass (ASM) divided by the weight (%), which is > 1 SD below the mean for young adults. The odds ratios (ORs) for sarcopenia were calculated using multiple logistic regression across the TG/HDL ratio quartiles (Q1: ≤ 1.4, Q2: 1.5–2.4, Q3: 2.5–3.8 and Q4: ≥ 3.9) after adjusting for confounding variables. Results The prevalence of sarcopenia significantly increased in accordance with TG/HDL ratio quartiles. Compared with the lowest quartile of the TG/HDL ratio, the corresponding OR (95% CI) of the highest quartile of the TG/HDL ratio for sarcopenia was 2.10 (1.12–3.91) after adjusting for age, body mass index (BMI), cigarette smoking, alcohol intake and physical activity. Conclusion TG/HDL ratio was positively related with a higher risk of sarcopenia in elderly Korean males.

Original languageEnglish
Pages (from-to)165-168
Number of pages4
JournalClinica Chimica Acta
Publication statusPublished - 2016 Dec 1


All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Clinical Biochemistry
  • Biochemistry, medical

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