Association between serum triglyceride to high-density lipoprotein cholesterol ratio and sarcopenia in elderly Korean males

The Korean National Health and Nutrition Examination Survey

Tae Ha Chung, Yu Jin Kwon, Jae Yong Shim, Yongjae Lee

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background We investigated the association between the triglycerides to high-density lipoprotein cholesterol (TG/HDL) ratio and sarcopenia in elderly Korean males. Methods We examined the relationship between the TG/HDL ratio and sarcopenia in 879 elderly males ≥ 60 years who participated in the 2010–2011 KNHANES. Sarcopenia was defined as an appendicular skeletal muscle mass (ASM) divided by the weight (%), which is > 1 SD below the mean for young adults. The odds ratios (ORs) for sarcopenia were calculated using multiple logistic regression across the TG/HDL ratio quartiles (Q1: ≤ 1.4, Q2: 1.5–2.4, Q3: 2.5–3.8 and Q4: ≥ 3.9) after adjusting for confounding variables. Results The prevalence of sarcopenia significantly increased in accordance with TG/HDL ratio quartiles. Compared with the lowest quartile of the TG/HDL ratio, the corresponding OR (95% CI) of the highest quartile of the TG/HDL ratio for sarcopenia was 2.10 (1.12–3.91) after adjusting for age, body mass index (BMI), cigarette smoking, alcohol intake and physical activity. Conclusion TG/HDL ratio was positively related with a higher risk of sarcopenia in elderly Korean males.

Original languageEnglish
Pages (from-to)165-168
Number of pages4
JournalClinica Chimica Acta
Volume463
DOIs
Publication statusPublished - 2016 Dec 1

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Sarcopenia
Nutrition Surveys
Nutrition
HDL Cholesterol
Triglycerides
Health
Serum
Odds Ratio
Confounding Factors (Epidemiology)
Tobacco Products
Muscle
Logistics
Young Adult
Skeletal Muscle
Body Mass Index
Logistic Models
Smoking
Alcohols
Exercise
Weights and Measures

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Clinical Biochemistry
  • Biochemistry, medical

Cite this

@article{5298e40ba10d47d39d4b3b8477da8769,
title = "Association between serum triglyceride to high-density lipoprotein cholesterol ratio and sarcopenia in elderly Korean males: The Korean National Health and Nutrition Examination Survey",
abstract = "Background We investigated the association between the triglycerides to high-density lipoprotein cholesterol (TG/HDL) ratio and sarcopenia in elderly Korean males. Methods We examined the relationship between the TG/HDL ratio and sarcopenia in 879 elderly males ≥ 60 years who participated in the 2010–2011 KNHANES. Sarcopenia was defined as an appendicular skeletal muscle mass (ASM) divided by the weight ({\%}), which is > 1 SD below the mean for young adults. The odds ratios (ORs) for sarcopenia were calculated using multiple logistic regression across the TG/HDL ratio quartiles (Q1: ≤ 1.4, Q2: 1.5–2.4, Q3: 2.5–3.8 and Q4: ≥ 3.9) after adjusting for confounding variables. Results The prevalence of sarcopenia significantly increased in accordance with TG/HDL ratio quartiles. Compared with the lowest quartile of the TG/HDL ratio, the corresponding OR (95{\%} CI) of the highest quartile of the TG/HDL ratio for sarcopenia was 2.10 (1.12–3.91) after adjusting for age, body mass index (BMI), cigarette smoking, alcohol intake and physical activity. Conclusion TG/HDL ratio was positively related with a higher risk of sarcopenia in elderly Korean males.",
author = "Chung, {Tae Ha} and Kwon, {Yu Jin} and Shim, {Jae Yong} and Yongjae Lee",
year = "2016",
month = "12",
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doi = "10.1016/j.cca.2016.10.032",
language = "English",
volume = "463",
pages = "165--168",
journal = "Clinica Chimica Acta",
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TY - JOUR

T1 - Association between serum triglyceride to high-density lipoprotein cholesterol ratio and sarcopenia in elderly Korean males

T2 - The Korean National Health and Nutrition Examination Survey

AU - Chung, Tae Ha

AU - Kwon, Yu Jin

AU - Shim, Jae Yong

AU - Lee, Yongjae

PY - 2016/12/1

Y1 - 2016/12/1

N2 - Background We investigated the association between the triglycerides to high-density lipoprotein cholesterol (TG/HDL) ratio and sarcopenia in elderly Korean males. Methods We examined the relationship between the TG/HDL ratio and sarcopenia in 879 elderly males ≥ 60 years who participated in the 2010–2011 KNHANES. Sarcopenia was defined as an appendicular skeletal muscle mass (ASM) divided by the weight (%), which is > 1 SD below the mean for young adults. The odds ratios (ORs) for sarcopenia were calculated using multiple logistic regression across the TG/HDL ratio quartiles (Q1: ≤ 1.4, Q2: 1.5–2.4, Q3: 2.5–3.8 and Q4: ≥ 3.9) after adjusting for confounding variables. Results The prevalence of sarcopenia significantly increased in accordance with TG/HDL ratio quartiles. Compared with the lowest quartile of the TG/HDL ratio, the corresponding OR (95% CI) of the highest quartile of the TG/HDL ratio for sarcopenia was 2.10 (1.12–3.91) after adjusting for age, body mass index (BMI), cigarette smoking, alcohol intake and physical activity. Conclusion TG/HDL ratio was positively related with a higher risk of sarcopenia in elderly Korean males.

AB - Background We investigated the association between the triglycerides to high-density lipoprotein cholesterol (TG/HDL) ratio and sarcopenia in elderly Korean males. Methods We examined the relationship between the TG/HDL ratio and sarcopenia in 879 elderly males ≥ 60 years who participated in the 2010–2011 KNHANES. Sarcopenia was defined as an appendicular skeletal muscle mass (ASM) divided by the weight (%), which is > 1 SD below the mean for young adults. The odds ratios (ORs) for sarcopenia were calculated using multiple logistic regression across the TG/HDL ratio quartiles (Q1: ≤ 1.4, Q2: 1.5–2.4, Q3: 2.5–3.8 and Q4: ≥ 3.9) after adjusting for confounding variables. Results The prevalence of sarcopenia significantly increased in accordance with TG/HDL ratio quartiles. Compared with the lowest quartile of the TG/HDL ratio, the corresponding OR (95% CI) of the highest quartile of the TG/HDL ratio for sarcopenia was 2.10 (1.12–3.91) after adjusting for age, body mass index (BMI), cigarette smoking, alcohol intake and physical activity. Conclusion TG/HDL ratio was positively related with a higher risk of sarcopenia in elderly Korean males.

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