Association between skeletal muscle mass and radial augmentation index in an elderly Korean population

Seung Won Lee, Yoosik Youm, Chang Oh Kim, Won Joon Lee, Wungrak Choi, Sang Hui Chu, Yeong Ran Park, HyeonChang Kim

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Increasing evidence supports the importance of maintaining skeletal muscle mass for cardiovascular health. However, there is limited data on the relationship between skeletal muscle mass and arterial stiffness targeting an elderly population. Thus, we investigated the association between skeletal muscle mass and arterial stiffness in an elderly Korean population. This study used data from the Korean Social Life, Health and Aging Project which started in 2011. In this cross-sectional study, 180 men (mean age 71.7) and 247 women (mean age 70.9) were included. Arm and leg muscle masses were measured by bioelectrical impedance analysis. Radial augmentation index, a noninvasive measure of arterial stiffness, was assessed by radial pulse wave analysis. The relationship between skeletal muscle mass and augmentation index was investigated by multiple linear regression analysis. In men, limb muscle mass was significantly and inversely associated with augmentation index (β=-1.07% per 1. kg muscle mass, p<. 0.001) when adjusted for age. This inverse association remained after additional adjustment for body mass index, systolic blood pressure, total cholesterol, high-density lipoprotein-cholesterol, fasting glucose, insulin, smoking and alcohol intake (β=-0.69%, p=0.019). In women, the inverse association between limb muscle mass and augmentation index was less prominent (β= -0.59%, p=0.030), and the association disappeared when fully adjusted (β=-0.32%, p=0.304). However, limb muscle mass was not associated with resting blood pressure either in men or women. Our results suggest that decreased skeletal muscle mass may affect arterial wall elasticity.

Original languageEnglish
Pages (from-to)49-55
Number of pages7
JournalArchives of Gerontology and Geriatrics
Volume59
Issue number1
DOIs
Publication statusPublished - 2014 Jan 1

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Skeletal Muscle
Vascular Stiffness
Muscles
Extremities
Population
Blood Pressure
Pulse Wave Analysis
Elasticity
Health
health
Electric Impedance
cross-sectional study
HDL Cholesterol
smoking
Linear Models
Fasting
Leg
regression analysis
Body Mass Index
Arm

All Science Journal Classification (ASJC) codes

  • Health(social science)
  • Ageing
  • Gerontology
  • Geriatrics and Gerontology

Cite this

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abstract = "Increasing evidence supports the importance of maintaining skeletal muscle mass for cardiovascular health. However, there is limited data on the relationship between skeletal muscle mass and arterial stiffness targeting an elderly population. Thus, we investigated the association between skeletal muscle mass and arterial stiffness in an elderly Korean population. This study used data from the Korean Social Life, Health and Aging Project which started in 2011. In this cross-sectional study, 180 men (mean age 71.7) and 247 women (mean age 70.9) were included. Arm and leg muscle masses were measured by bioelectrical impedance analysis. Radial augmentation index, a noninvasive measure of arterial stiffness, was assessed by radial pulse wave analysis. The relationship between skeletal muscle mass and augmentation index was investigated by multiple linear regression analysis. In men, limb muscle mass was significantly and inversely associated with augmentation index (β=-1.07{\%} per 1. kg muscle mass, p<. 0.001) when adjusted for age. This inverse association remained after additional adjustment for body mass index, systolic blood pressure, total cholesterol, high-density lipoprotein-cholesterol, fasting glucose, insulin, smoking and alcohol intake (β=-0.69{\%}, p=0.019). In women, the inverse association between limb muscle mass and augmentation index was less prominent (β= -0.59{\%}, p=0.030), and the association disappeared when fully adjusted (β=-0.32{\%}, p=0.304). However, limb muscle mass was not associated with resting blood pressure either in men or women. Our results suggest that decreased skeletal muscle mass may affect arterial wall elasticity.",
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Association between skeletal muscle mass and radial augmentation index in an elderly Korean population. / Lee, Seung Won; Youm, Yoosik; Kim, Chang Oh; Lee, Won Joon; Choi, Wungrak; Chu, Sang Hui; Park, Yeong Ran; Kim, HyeonChang.

In: Archives of Gerontology and Geriatrics, Vol. 59, No. 1, 01.01.2014, p. 49-55.

Research output: Contribution to journalArticle

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AU - Lee, Seung Won

AU - Youm, Yoosik

AU - Kim, Chang Oh

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AU - Choi, Wungrak

AU - Chu, Sang Hui

AU - Park, Yeong Ran

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