Association between the A1 allele of the DRD2 gene and reduced verbal abilities in adolescence and early adulthood

Kevin M. Beaver, Matt Delisi, Michael G. Vaughn, John Paul Wright

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Behavioral genetic research has consistently revealed that genetic factors explain at least one half of the variance in measures of cognitive skills. However, the specific DNA markers involved in the etiology of cognitive abilities have remained elusive. The current study examined the association between the TaqI polymorphism in the dopamine D2 receptor gene (DRD2) and verbal skills. Analysis of data drawn from the National Longitudinal Study of Adolescent Health (Add Health) revealed that the A1 allele was associated with group membership in high-, average-, and low-verbal skills groups for Caucasians. The results suggest that DRD2 may be related to domain specific cognitive abilities, such as verbal skills.

Original languageEnglish
Pages (from-to)827-830
Number of pages4
JournalJournal of Neural Transmission
Volume117
Issue number7
DOIs
Publication statusPublished - 2010 Jul

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health
  • Biological Psychiatry

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