Association between the National Cancer Screening Programme (NSCP) for gastric cancer and oesophageal cancer mortality

for the Big Data Research Group (BDRG) of the Korean Society of Gastroenterology (KSG)

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4 Citations (Scopus)


Background: The aim was to evaluate whether this gastric cancer-screening programme was effective in reducing oesophageal cancer mortality. Methods: A population-based retrospective cohort study was conducted using the Korean National Cancer Screening Programme (NCSP) database. The study cohort comprised 16,969 oesophageal cancer patients who had been diagnosed in 2007–2014. We analysed the association between the history of NSCP for gastric cancer and oesophageal cancer mortality. Results: Compared with never-screened subjects, ever-screened subjects had an overall HR for oesophageal cancer mortality of 0.647 (95% CI, 0.617–0.679). According to the time interval since screening, the HRs of death were 0.731 (95% CI, 0.667–0.801) for 6–11 months, 0.635 (95% CI, 0.594–0.679) for 12–23 months, 0.564 (95% CI, 0.522–0.610) for 24–35 months and 0.742 (95% CI, 0.679–0.810) for ≥36 months. According to the last screening modality, the HRs of death were 0.497 (95% CI, 0.464–0.531) for upper endoscopy, and 0.792 (95% CI, 0.749–0.838) for UGIS. Upper endoscopy reduced the mortality consistently in all age groups over 50 years, whereas UGIS could not. Conclusion: The NCSP for gastric cancer was effective in reducing the mortality of oesophageal cancer, and upper endoscopy was superior to UGIS.

Original languageEnglish
Pages (from-to)480-486
Number of pages7
JournalBritish journal of cancer
Issue number3
Publication statusPublished - 2020 Aug 4

Bibliographical note

Funding Information:
Funding information This study was supported by grants from the research fund from the Korean Society of Gastroenterology and the National R&D Programme for Cancer Control (1720200) and the Korean National Health Clinical Research (NHCR) project (HC16C2320), Ministry of Health and Welfare, Republic of Korea.

Publisher Copyright:
© 2020, The Author(s), under exclusive licence to Cancer Research UK.

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research


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