Association of air pollution with increased incidence of ventricular tachyarrhythmias recorded by implantable cardioverter defibrillators: Vulnerable patients to air pollution

In Soo Kim, Jungwoo Sohn, Seung Jun Lee, Jin Kyu Park, Jae Sun Uhm, Hui Nam Pak, Moon Hyoung Lee, Changsoo Kim, Boyoung Joung

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background This study investigated the acute effects of exposure to air pollution on ventricular tachyarrhythmias (VTAs) in an East Asian population. The association between air pollution and VTA has not yet been studied in an East Asian country affected by the Asian dust phenomenon, which worsens air quality. Methods The study cohort consisted of 160patients with implantable cardioverter defibrillator (ICD) devices in the Seoul metropolitan area who were followed for 5.5 ± 3.8 years. We used ICD records of VTAs and matched these with hourly measurements of air pollutant concentrations and meteorological data. Fine particle mass and gaseous air pollution plus temperature and relative humidity were measured hourly during the study period. Results During the study period, 1064 VTA events including 204 instances of ventricular fibrillation (VF) were observed. We found a statistically significant association between overall VTA events and SO2 (lag 24 h; OR 1.49, 95%CI 1.16–1.92, p = 0.002), PM10 (lag 2 h; OR 2.56, 95%CI 2.03–3.23, p < 0.001), NO2 (lag 24 h; OR 1.25, 95%CI 1.19–1.31, p < 0.001) and CO (lag 24 h; OR 1.05, 95%CI 1.02–1.08, p = 0.003). Sustained ventricular tachycardia or VF was also independently associated with SO2, PM10, NO2 and CO (all p < 0.01). Exposures to SO2, PM10, NO2, and CO (all p < 0.01) were significantly related to overall VTAs, especially in patients with structural heart disease (SHD). Conclusions Associations between air pollution and VTA were observed in a metropolitan area of an East Asian country. Exposures to SO2, PM10, NO2, and CO were significantly associated with VTAs in ICD patients with SHD.

Original languageEnglish
Pages (from-to)214-220
Number of pages7
JournalInternational Journal of Cardiology
Volume240
DOIs
Publication statusPublished - 2017 Aug 1

Fingerprint

Implantable Defibrillators
Air Pollution
Tachycardia
Incidence
Carbon Monoxide
Ventricular Fibrillation
Heart Diseases
Air Pollutants
Ventricular Tachycardia
Humidity
Dust
Cohort Studies
Air
Equipment and Supplies
Temperature

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

@article{e440b3c7d88844c9a6e7d6a61173c41a,
title = "Association of air pollution with increased incidence of ventricular tachyarrhythmias recorded by implantable cardioverter defibrillators: Vulnerable patients to air pollution",
abstract = "Background This study investigated the acute effects of exposure to air pollution on ventricular tachyarrhythmias (VTAs) in an East Asian population. The association between air pollution and VTA has not yet been studied in an East Asian country affected by the Asian dust phenomenon, which worsens air quality. Methods The study cohort consisted of 160patients with implantable cardioverter defibrillator (ICD) devices in the Seoul metropolitan area who were followed for 5.5 ± 3.8 years. We used ICD records of VTAs and matched these with hourly measurements of air pollutant concentrations and meteorological data. Fine particle mass and gaseous air pollution plus temperature and relative humidity were measured hourly during the study period. Results During the study period, 1064 VTA events including 204 instances of ventricular fibrillation (VF) were observed. We found a statistically significant association between overall VTA events and SO2 (lag 24 h; OR 1.49, 95{\%}CI 1.16–1.92, p = 0.002), PM10 (lag 2 h; OR 2.56, 95{\%}CI 2.03–3.23, p < 0.001), NO2 (lag 24 h; OR 1.25, 95{\%}CI 1.19–1.31, p < 0.001) and CO (lag 24 h; OR 1.05, 95{\%}CI 1.02–1.08, p = 0.003). Sustained ventricular tachycardia or VF was also independently associated with SO2, PM10, NO2 and CO (all p < 0.01). Exposures to SO2, PM10, NO2, and CO (all p < 0.01) were significantly related to overall VTAs, especially in patients with structural heart disease (SHD). Conclusions Associations between air pollution and VTA were observed in a metropolitan area of an East Asian country. Exposures to SO2, PM10, NO2, and CO were significantly associated with VTAs in ICD patients with SHD.",
author = "Kim, {In Soo} and Jungwoo Sohn and Lee, {Seung Jun} and Park, {Jin Kyu} and Uhm, {Jae Sun} and Pak, {Hui Nam} and Lee, {Moon Hyoung} and Changsoo Kim and Boyoung Joung",
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month = "8",
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doi = "10.1016/j.ijcard.2017.03.122",
language = "English",
volume = "240",
pages = "214--220",
journal = "International Journal of Cardiology",
issn = "0167-5273",
publisher = "Elsevier Ireland Ltd",

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Association of air pollution with increased incidence of ventricular tachyarrhythmias recorded by implantable cardioverter defibrillators : Vulnerable patients to air pollution. / Kim, In Soo; Sohn, Jungwoo; Lee, Seung Jun; Park, Jin Kyu; Uhm, Jae Sun; Pak, Hui Nam; Lee, Moon Hyoung; Kim, Changsoo; Joung, Boyoung.

In: International Journal of Cardiology, Vol. 240, 01.08.2017, p. 214-220.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Association of air pollution with increased incidence of ventricular tachyarrhythmias recorded by implantable cardioverter defibrillators

T2 - Vulnerable patients to air pollution

AU - Kim, In Soo

AU - Sohn, Jungwoo

AU - Lee, Seung Jun

AU - Park, Jin Kyu

AU - Uhm, Jae Sun

AU - Pak, Hui Nam

AU - Lee, Moon Hyoung

AU - Kim, Changsoo

AU - Joung, Boyoung

PY - 2017/8/1

Y1 - 2017/8/1

N2 - Background This study investigated the acute effects of exposure to air pollution on ventricular tachyarrhythmias (VTAs) in an East Asian population. The association between air pollution and VTA has not yet been studied in an East Asian country affected by the Asian dust phenomenon, which worsens air quality. Methods The study cohort consisted of 160patients with implantable cardioverter defibrillator (ICD) devices in the Seoul metropolitan area who were followed for 5.5 ± 3.8 years. We used ICD records of VTAs and matched these with hourly measurements of air pollutant concentrations and meteorological data. Fine particle mass and gaseous air pollution plus temperature and relative humidity were measured hourly during the study period. Results During the study period, 1064 VTA events including 204 instances of ventricular fibrillation (VF) were observed. We found a statistically significant association between overall VTA events and SO2 (lag 24 h; OR 1.49, 95%CI 1.16–1.92, p = 0.002), PM10 (lag 2 h; OR 2.56, 95%CI 2.03–3.23, p < 0.001), NO2 (lag 24 h; OR 1.25, 95%CI 1.19–1.31, p < 0.001) and CO (lag 24 h; OR 1.05, 95%CI 1.02–1.08, p = 0.003). Sustained ventricular tachycardia or VF was also independently associated with SO2, PM10, NO2 and CO (all p < 0.01). Exposures to SO2, PM10, NO2, and CO (all p < 0.01) were significantly related to overall VTAs, especially in patients with structural heart disease (SHD). Conclusions Associations between air pollution and VTA were observed in a metropolitan area of an East Asian country. Exposures to SO2, PM10, NO2, and CO were significantly associated with VTAs in ICD patients with SHD.

AB - Background This study investigated the acute effects of exposure to air pollution on ventricular tachyarrhythmias (VTAs) in an East Asian population. The association between air pollution and VTA has not yet been studied in an East Asian country affected by the Asian dust phenomenon, which worsens air quality. Methods The study cohort consisted of 160patients with implantable cardioverter defibrillator (ICD) devices in the Seoul metropolitan area who were followed for 5.5 ± 3.8 years. We used ICD records of VTAs and matched these with hourly measurements of air pollutant concentrations and meteorological data. Fine particle mass and gaseous air pollution plus temperature and relative humidity were measured hourly during the study period. Results During the study period, 1064 VTA events including 204 instances of ventricular fibrillation (VF) were observed. We found a statistically significant association between overall VTA events and SO2 (lag 24 h; OR 1.49, 95%CI 1.16–1.92, p = 0.002), PM10 (lag 2 h; OR 2.56, 95%CI 2.03–3.23, p < 0.001), NO2 (lag 24 h; OR 1.25, 95%CI 1.19–1.31, p < 0.001) and CO (lag 24 h; OR 1.05, 95%CI 1.02–1.08, p = 0.003). Sustained ventricular tachycardia or VF was also independently associated with SO2, PM10, NO2 and CO (all p < 0.01). Exposures to SO2, PM10, NO2, and CO (all p < 0.01) were significantly related to overall VTAs, especially in patients with structural heart disease (SHD). Conclusions Associations between air pollution and VTA were observed in a metropolitan area of an East Asian country. Exposures to SO2, PM10, NO2, and CO were significantly associated with VTAs in ICD patients with SHD.

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