Association of hearing impairment with chronic kidney disease: A cross-sectional study of the Korean general population

Young Joon Seo, Sangbaek Koh, Tae Hyung Ha, Tae Hoon Gong, Jeong Pyo Bong, Dongjoon Park, Sangyoo Park

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Background: We aimed to evaluate the association between hearing impairment and the prevalence of chronic kidney disease (CKD) in the largest population-based cross-sectional study to date. Methods: This cross-sectional study was based on the Korean National Health and Nutritional Examination Survey (KNHANES). It included 5226 participants ≥19 years of age whose estimated glomerular filtration rate (eGFR) and hearing threshold had been measured. We diagnosed CKD as an eGFR∈<60 mL/min/1.73 m2. The participants were also evaluated for the presence of other contributing factors related to kidney dysfunction. We divided the participants at the 40-dB threshold into hearing-impairment and no-hearing-impairment groups, using the average threshold of all six frequencies (500, 1000, 2000, 3000, 4000, and 6000 Hz) for both ears. Results: The odds of hearing impairment was 1.25 times higher (95 % confidence interval: 1.12-1.64, p-value∈<∈0.001) in participants with an eGFR∈<60 mL/min/1.73 m2 than in those with an eGFR∈≥60 mL/min/1.73 m2 after adjustments for age, sex, smoking, alcohol, body mass index, diabetes mellitus, hypertension, dyslipidemia, and microalbuminuria. Among the risk parameters of CKD associated with hearing impairment, linear regression analysis adjusted for age and sex determined that each increase of serum creatinine or blood pressure was positively associated with an increase in hearing threshold (p-value∈<∈0.01). Conclusion: The odds of hearing impairment were greater with lower eGFR than with normal eGFR. Individuals with CKD were more likely to also have hearing impairment. We recommend screening the hearing of patients with CKD to provide earlier identification of hearing impairment and earlier intervention, thereby preventing progression of hearing impairment and providing appropriate treatment strategies.

Original languageEnglish
Article number154
JournalBMC Nephrology
Volume16
Issue number1
DOIs
Publication statusPublished - 2015 Sep 16

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Chronic Renal Insufficiency
Hearing Loss
Cross-Sectional Studies
Glomerular Filtration Rate
Population
Hearing
Nutrition Surveys
Dyslipidemias
Ear
Linear Models
Creatinine
Diabetes Mellitus
Body Mass Index
Smoking
Regression Analysis
Alcohols
Confidence Intervals
Blood Pressure
Hypertension
Kidney

All Science Journal Classification (ASJC) codes

  • Nephrology

Cite this

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abstract = "Background: We aimed to evaluate the association between hearing impairment and the prevalence of chronic kidney disease (CKD) in the largest population-based cross-sectional study to date. Methods: This cross-sectional study was based on the Korean National Health and Nutritional Examination Survey (KNHANES). It included 5226 participants ≥19 years of age whose estimated glomerular filtration rate (eGFR) and hearing threshold had been measured. We diagnosed CKD as an eGFR∈<60 mL/min/1.73 m2. The participants were also evaluated for the presence of other contributing factors related to kidney dysfunction. We divided the participants at the 40-dB threshold into hearing-impairment and no-hearing-impairment groups, using the average threshold of all six frequencies (500, 1000, 2000, 3000, 4000, and 6000 Hz) for both ears. Results: The odds of hearing impairment was 1.25 times higher (95 {\%} confidence interval: 1.12-1.64, p-value∈<∈0.001) in participants with an eGFR∈<60 mL/min/1.73 m2 than in those with an eGFR∈≥60 mL/min/1.73 m2 after adjustments for age, sex, smoking, alcohol, body mass index, diabetes mellitus, hypertension, dyslipidemia, and microalbuminuria. Among the risk parameters of CKD associated with hearing impairment, linear regression analysis adjusted for age and sex determined that each increase of serum creatinine or blood pressure was positively associated with an increase in hearing threshold (p-value∈<∈0.01). Conclusion: The odds of hearing impairment were greater with lower eGFR than with normal eGFR. Individuals with CKD were more likely to also have hearing impairment. We recommend screening the hearing of patients with CKD to provide earlier identification of hearing impairment and earlier intervention, thereby preventing progression of hearing impairment and providing appropriate treatment strategies.",
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Association of hearing impairment with chronic kidney disease : A cross-sectional study of the Korean general population. / Seo, Young Joon; Koh, Sangbaek; Ha, Tae Hyung; Gong, Tae Hoon; Bong, Jeong Pyo; Park, Dongjoon; Park, Sangyoo.

In: BMC Nephrology, Vol. 16, No. 1, 154, 16.09.2015.

Research output: Contribution to journalArticle

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AU - Seo, Young Joon

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AB - Background: We aimed to evaluate the association between hearing impairment and the prevalence of chronic kidney disease (CKD) in the largest population-based cross-sectional study to date. Methods: This cross-sectional study was based on the Korean National Health and Nutritional Examination Survey (KNHANES). It included 5226 participants ≥19 years of age whose estimated glomerular filtration rate (eGFR) and hearing threshold had been measured. We diagnosed CKD as an eGFR∈<60 mL/min/1.73 m2. The participants were also evaluated for the presence of other contributing factors related to kidney dysfunction. We divided the participants at the 40-dB threshold into hearing-impairment and no-hearing-impairment groups, using the average threshold of all six frequencies (500, 1000, 2000, 3000, 4000, and 6000 Hz) for both ears. Results: The odds of hearing impairment was 1.25 times higher (95 % confidence interval: 1.12-1.64, p-value∈<∈0.001) in participants with an eGFR∈<60 mL/min/1.73 m2 than in those with an eGFR∈≥60 mL/min/1.73 m2 after adjustments for age, sex, smoking, alcohol, body mass index, diabetes mellitus, hypertension, dyslipidemia, and microalbuminuria. Among the risk parameters of CKD associated with hearing impairment, linear regression analysis adjusted for age and sex determined that each increase of serum creatinine or blood pressure was positively associated with an increase in hearing threshold (p-value∈<∈0.01). Conclusion: The odds of hearing impairment were greater with lower eGFR than with normal eGFR. Individuals with CKD were more likely to also have hearing impairment. We recommend screening the hearing of patients with CKD to provide earlier identification of hearing impairment and earlier intervention, thereby preventing progression of hearing impairment and providing appropriate treatment strategies.

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