Asymmetric dihydroxylation of enynes

Kyu-Sung Jeong, Peter Sjö, K. Barry Sharpless

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

Catalytic asymmetric dihydroxylations of 1,3-enynes were studied using 9-O-(9′-phenanthryl) dihydroquinidine (PHN-DHQD) 1 and 1,4-bis-(9-O-dihydroquinidine) phthalazine (DHQD2-PHAL) 2. Terminal olefins showed moderate (38-79% ee) and trans-disubstituted olefins high enantioselectivities (73 - 97% ee).

Original languageEnglish
Pages (from-to)3833-3836
Number of pages4
JournalTetrahedron Letters
Volume33
Issue number27
DOIs
Publication statusPublished - 1992 Jan 1

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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