Asymmetric total synthesis of (+)-brefeldin A: Intramolecular epoxide-opening/RCM strategy

Myung Yeol Kim, Hyemi Kim, Jinsung Tae

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

A highly efficient asymmetric total synthesis of (+)-brefeldin A was accomplished by using intramolecular epoxide opening of an epoxy allylsilane and RCM reaction for the constructions of the cyclopentane and macrocyclic lactone rings of (+)-brefeldin A, respectively.

Original languageEnglish
Pages (from-to)1303-1306
Number of pages4
JournalSynlett
Issue number8
DOIs
Publication statusPublished - 2009 May 1

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Brefeldin A
Epoxy Compounds
Cyclopentanes
Lactones
allylsilane

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

Cite this

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abstract = "A highly efficient asymmetric total synthesis of (+)-brefeldin A was accomplished by using intramolecular epoxide opening of an epoxy allylsilane and RCM reaction for the constructions of the cyclopentane and macrocyclic lactone rings of (+)-brefeldin A, respectively.",
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Asymmetric total synthesis of (+)-brefeldin A : Intramolecular epoxide-opening/RCM strategy. / Kim, Myung Yeol; Kim, Hyemi; Tae, Jinsung.

In: Synlett, No. 8, 01.05.2009, p. 1303-1306.

Research output: Contribution to journalArticle

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