Asymmetric total synthesis of (+)-brefeldin A: Intramolecular epoxide-opening/RCM strategy

Myung Yeol Kim, Hyemi Kim, Jinsung Tae

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17 Citations (Scopus)

Abstract

A highly efficient asymmetric total synthesis of (+)-brefeldin A was accomplished by using intramolecular epoxide opening of an epoxy allylsilane and RCM reaction for the constructions of the cyclopentane and macrocyclic lactone rings of (+)-brefeldin A, respectively.

Original languageEnglish
Pages (from-to)1303-1306
Number of pages4
JournalSynlett
Issue number8
DOIs
Publication statusPublished - 2009 May 1

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All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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