Asymmetric total synthesis of (-)-galanthamine via intramolecular heck reaction of conjugated diene

Juhee Choi; Hyunseok Kim; Sangyun Park; Jinsung Tae

doi:10.1055/s-0032-1317791

Asymmetric total synthesis of (-)-galanthamine via intramolecular heck reaction of conjugated diene

Juhee Choi, Hyunseok Kim, Sangyun Park, Jinsung Tae

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

Asymmetric total synthesis of (-)-galanthamine was accomplished starting from an epoxide. Intramolecular Heck reaction of a conjugated diene system was employed to construct the key quaternary carbon center. The cyclohexene-1,3-diol unit of (-)-galanthamine is derived from an optically active epoxy alkenol.

Original language	English
Article number	ST-2012-U1008-L
Pages (from-to)	379-382
Number of pages	4
Journal	Synlett
Volume	24
Issue number	3
DOIs	https://doi.org/10.1055/s-0032-1317791
Publication status	Published - 2013

All Science Journal Classification (ASJC) codes

Organic Chemistry

Access to Document

10.1055/s-0032-1317791

Cite this

@article{13502da6fa59421e9354769aff7e2da6,

title = "Asymmetric total synthesis of (-)-galanthamine via intramolecular heck reaction of conjugated diene",

abstract = "Asymmetric total synthesis of (-)-galanthamine was accomplished starting from an epoxide. Intramolecular Heck reaction of a conjugated diene system was employed to construct the key quaternary carbon center. The cyclohexene-1,3-diol unit of (-)-galanthamine is derived from an optically active epoxy alkenol.",

author = "Juhee Choi and Hyunseok Kim and Sangyun Park and Jinsung Tae",

year = "2013",

doi = "10.1055/s-0032-1317791",

language = "English",

volume = "24",

pages = "379--382",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "3",

}

TY - JOUR

T1 - Asymmetric total synthesis of (-)-galanthamine via intramolecular heck reaction of conjugated diene

AU - Choi, Juhee

AU - Kim, Hyunseok

AU - Park, Sangyun

AU - Tae, Jinsung

PY - 2013

Y1 - 2013

N2 - Asymmetric total synthesis of (-)-galanthamine was accomplished starting from an epoxide. Intramolecular Heck reaction of a conjugated diene system was employed to construct the key quaternary carbon center. The cyclohexene-1,3-diol unit of (-)-galanthamine is derived from an optically active epoxy alkenol.

AB - Asymmetric total synthesis of (-)-galanthamine was accomplished starting from an epoxide. Intramolecular Heck reaction of a conjugated diene system was employed to construct the key quaternary carbon center. The cyclohexene-1,3-diol unit of (-)-galanthamine is derived from an optically active epoxy alkenol.

UR - http://www.scopus.com/inward/record.url?scp=84872178144&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84872178144&partnerID=8YFLogxK

U2 - 10.1055/s-0032-1317791

DO - 10.1055/s-0032-1317791

M3 - Article

AN - SCOPUS:84872178144

SN - 0936-5214

VL - 24

SP - 379

EP - 382

JO - Synlett

JF - Synlett

IS - 3

M1 - ST-2012-U1008-L

ER -

Asymmetric total synthesis of (-)-galanthamine via intramolecular heck reaction of conjugated diene

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this