Automatic coronary artery segmentation using active search for branches and seemingly disconnected vessel segments from coronary CT angiography

Dongjin Han, Hackjoon Shim, Byunghwan Jeon, Yeonggul Jang, Youngtaek Hong, Sunghee Jung, Seongmin Ha, Hyuk Jae Chang

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

We propose a Bayesian tracking and segmentation method of coronary arteries on coronary computed tomographic angiography (CCTA). The geometry of coronary arteries including lumen boundary is estimated in Maximum A Posteriori (MAP) framework. Three consecutive sphere based filtering is combined with a stochastic process that is based on the similarity of the consecutive local neighborhood voxels and the geometric constraint of a vessel. It is also founded on the prior knowledge that an artery can be seen locally disconnected and consist of branches which may be seemingly disconnected due to plaque build up. For such problem, an active search method is proposed to find branches and seemingly disconnected but actually connected vessel segments. Several new measures have been developed for branch detection, disconnection check and planar vesselness measure. Using public domain Rotterdam CT dataset, the accuracy of extracted centerline is demonstrated and automatic reconstruction of coronary artery mesh is shown.

Original languageEnglish
Article numbere0156837
JournalPloS one
Volume11
Issue number8
DOIs
Publication statusPublished - 2016 Aug

Bibliographical note

Funding Information:
This work was supported by the ICT RandD program of MSIP/IITP (10044910, Development of Multi-modality Imaging and 3D Simulation-Based Integrative Diagnosis-Treatment Support Software System for Cardiovascular Diseases) Korea. This work was supported by Institute for Information and communications Technology Promotion(IITP) grant funded by the Korea government(MSIP) (No.R0101-16-0171, Development of Multi-modality Imaging and 3D Simulation-Based Integrative Diagnosis-Treatment Support Software System for Cardiovascular Diseases).

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • General

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