Automatic detection and segmentation of lumbar vertebrae from X-ray images for compression fracture evaluation

Kang Cheol Kim, Hyun Cheol Cho, Tae Jun Jang, Jong Mun Choi, Jin Keun Seo

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

For compression fracture detection and evaluation, an automatic X-ray image segmentation technique that combines deep-learning and level-set methods is proposed. Automatic segmentation is much more difficult for X-ray images than for CT or MRI images because they contain overlapping shadows of thoracoabdominal structures including lungs, bowel gases, and other bony structures such as ribs. Additional difficulties include unclear object boundaries, the complex shape of the vertebra, inter-patient variability, and variations in image contrast. Accordingly, a structured hierarchical segmentation method is presented that combines the advantages of two deep-learning methods. Pose-driven learning is used to selectively identify the five lumbar vertebrae in an accurate and robust manner. With knowledge of the vertebral positions, M-net is employed to segment the individual vertebra. Finally, fine-tuning segmentation is applied by combining the level-set method with the previously obtained segmentation results. The performance of the proposed method was validated by 160 lumbar X-ray images, resulting in a mean Dice similarity metric of 91.60±2.22%. The results show that the proposed method achieves accurate and robust identification of each lumbar vertebra and fine segmentation of individual vertebra.

Original languageEnglish
Article number105833
JournalComputer Methods and Programs in Biomedicine
Volume200
DOIs
Publication statusPublished - 2021 Mar

Bibliographical note

Funding Information:
K.C.K. was supported by the National Research Foundation of Korea (NRF) grant 2017R1E1A1A03070653 . H.C.C., T.J.J., and J.K.S. were supported by the NRF grant 2015R1A5A1009350.

Publisher Copyright:
© 2020

All Science Journal Classification (ASJC) codes

  • Software
  • Computer Science Applications
  • Health Informatics

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