Automatic Identification of Interictal Epileptiform Discharges in Secondary Generalized Epilepsy

Won Du Chang, Ho Seung Cha, Chany Lee, Hoon Chul Kang, Chang Hwan Im

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Ictal epileptiform discharges (EDs) are characteristic signal patterns of scalp electroencephalogram (EEG) or intracranial EEG (iEEG) recorded from patients with epilepsy, which assist with the diagnosis and characterization of various types of epilepsy. The EEG signal, however, is often recorded from patients with epilepsy for a long period of time, and thus detection and identification of EDs have been a burden on medical doctors. This paper proposes a new method for automatic identification of two types of EDs, repeated sharp-waves (sharps), and runs of sharp-And-slow-waves (SSWs), which helps to pinpoint epileptogenic foci in secondary generalized epilepsy such as Lennox-Gastaut syndrome (LGS). In the experiments with iEEG data acquired from a patient with LGS, our proposed method detected EDs with an accuracy of 93.76% and classified three different signal patterns with a mean classification accuracy of 87.69%, which was significantly higher than that of a conventional wavelet-based method. Our study shows that it is possible to successfully detect and discriminate sharps and SSWs from background EEG activity using our proposed method.

Original languageEnglish
Article number8701973
JournalComputational and Mathematical Methods in Medicine
Volume2016
DOIs
Publication statusPublished - 2016 Jan 1

Fingerprint

Generalized Epilepsy
Epilepsy
Electroencephalography
Scalp
Period of time
Stroke
Wavelets
Electroencephalogram
Experiment
Experiments
Lennox Gastaut Syndrome

All Science Journal Classification (ASJC) codes

  • Modelling and Simulation
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Applied Mathematics

Cite this

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Automatic Identification of Interictal Epileptiform Discharges in Secondary Generalized Epilepsy. / Chang, Won Du; Cha, Ho Seung; Lee, Chany; Kang, Hoon Chul; Im, Chang Hwan.

In: Computational and Mathematical Methods in Medicine, Vol. 2016, 8701973, 01.01.2016.

Research output: Contribution to journalArticle

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AU - Kang, Hoon Chul

AU - Im, Chang Hwan

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