Bacterial recognition of silicon nanowire arrays

Hoon Eui Jeong, Ilsoo Kim, Pierre Karam, Heon Jin Choi, Peidong Yang

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abstract

Understanding how living cells interact with nanostructures is integral to a better understanding of the fundamental principles of biology and the development of next-generation biomedical/bioenergy devices. Recent studies have demonstrated that mammalian cells can recognize nanoscale topographies and respond to these structures. From this perspective, there is a growing recognition that nanostructures, along with their specific physicochemical properties, can also be used to regulate the responses and motions of bacterial cells. Here, by utilizing a well-defined silicon nanowire array platform and single-cell imaging, we present direct evidence that Shewanella oneidensis MR-1 can recognize nanoscale structures and that their swimming patterns and initial attachment locations are strongly influenced by the presence of nanowires on a surface. Analyses of bacterial trajectories revealed that MR-1 cells exhibited a confined diffusion mode in the presence of nanowires and showed preferential attachment to the nanowires, whereas a superdiffusion mode was observed in the absence of nanowires. These results demonstrate that nanoscale topography can affect bacterial movement and attachment and play an important role during the early stages of biofilm formation.

Original languageEnglish
Pages (from-to)2864-2869
Number of pages6
JournalNano letters
Volume13
Issue number6
DOIs
Publication statusPublished - 2013 Jun 12

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanical Engineering

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    Jeong, H. E., Kim, I., Karam, P., Choi, H. J., & Yang, P. (2013). Bacterial recognition of silicon nanowire arrays. Nano letters, 13(6), 2864-2869. https://doi.org/10.1021/nl401205b