We propose a robust method to simultaneously localize multiple objects in cardiac computed tomography angiography (CTA) images. The relative prior distributions of the multiple objects in the three-dimensional (3D) space can be obtained through integrating the geometric morphological relationship of each target object to some reference objects. In cardiac CTA images, the cross-sections of ascending and descending aorta can play the role of the reference objects. We employed the maximum a posteriori (MAP) estimator that utilizes anatomic prior knowledge to address this problem of localizing multiple objects. We propose a new feature for each pixel using the relative distances, which can define any objects that have unclear boundaries. Our experimental results targeting four pulmonary veins (PVs) and the left atrial appendage (LAA) in cardiac CTA images demonstrate the robustness of the proposed method. The method could also be extended to localize other multiple objects in different applications.
Bibliographical noteFunding Information:
This work was supported by the Korea Medical Device Development Fund grant funded by the Korea government (the Ministry of Science and ICT, the Ministry of Trade, Industry and Energy, the Ministry of Health & Welfare, Republic of Korea, the Ministry of Food and Drug Safety) (Project Number: 202016B02) and supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (1345322865).
All Science Journal Classification (ASJC) codes
- Physics and Astronomy(all)