TY - GEN
T1 - Bayesian validation of fuzzy clustering for analysis of yeast cell cycle data
AU - Kim, Kyung Joong
AU - Yoo, Si Ho
AU - Cho, Sung Bae
PY - 2005
Y1 - 2005
N2 - Clustering for the analysis of the gene expression profiles has been used for identifying the functions of the genes and of unknown genes. Since the genes usually belong to multiple functional families, fuzzy clustering methods are more appropriate than the conventional hard clustering methods. However, it is still required to devise natural way to measure the quality of the cluster partitions that are obtained by fuzzy clustering. In this paper, a Bayesian validation method of selecting a fuzzy partition with the largest posterior probability given the dataset is proposed to evaluate the fuzzy partitions effectively. Analysis of yeast cell-cycle data follows to show the usefulness of the proposed method.
AB - Clustering for the analysis of the gene expression profiles has been used for identifying the functions of the genes and of unknown genes. Since the genes usually belong to multiple functional families, fuzzy clustering methods are more appropriate than the conventional hard clustering methods. However, it is still required to devise natural way to measure the quality of the cluster partitions that are obtained by fuzzy clustering. In this paper, a Bayesian validation method of selecting a fuzzy partition with the largest posterior probability given the dataset is proposed to evaluate the fuzzy partitions effectively. Analysis of yeast cell-cycle data follows to show the usefulness of the proposed method.
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U2 - 10.1007/11553939_110
DO - 10.1007/11553939_110
M3 - Conference contribution
AN - SCOPUS:33745319500
SN - 3540288961
SN - 9783540288961
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 777
EP - 784
BT - Knowledge-Based Intelligent Information and Engineering Systems - 9th International Conference, KES 2005, Proceedings
PB - Springer Verlag
T2 - 9th International Conference on Knowledge-Based Intelligent Information and Engineering Systems, KES 2005
Y2 - 14 September 2005 through 16 September 2005
ER -