BCl 3 -promoted synthesis of benzofurans

Ikyon Kim, Sei Hee Lee, Sunkyung Lee

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Lewis acidic nature of boron trichloride (BCl 3 ) to coordinate to the carbonyl functionality was exploited for the synthesis of benzofurans via dehydrative cyclization. This mild and efficient procedure allowed for facile access to a number of highly substituted benzofurans in a regioselective manner. The structural requirement for the successful cyclodehydration was examined in the cases, where competitive demethylation could occur.

Original languageEnglish
Pages (from-to)6579-6584
Number of pages6
JournalTetrahedron Letters
Volume49
Issue number46
DOIs
Publication statusPublished - 2008 Nov 10

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Benzofurans
Cyclization

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Kim, Ikyon ; Lee, Sei Hee ; Lee, Sunkyung. / BCl 3 -promoted synthesis of benzofurans In: Tetrahedron Letters. 2008 ; Vol. 49, No. 46. pp. 6579-6584.
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BCl 3 -promoted synthesis of benzofurans . / Kim, Ikyon; Lee, Sei Hee; Lee, Sunkyung.

In: Tetrahedron Letters, Vol. 49, No. 46, 10.11.2008, p. 6579-6584.

Research output: Contribution to journalArticle

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