Behçet's disease

Gastrointestinal involvement

JaeHee Cheon, Aykut Ferhat Çelik, Won Ho Kim

Research output: Chapter in Book/Report/Conference proceedingChapter

21 Citations (Scopus)

Abstract

Reports indicate that the prevalence of gastrointestinal involvement of Behçet's disease (BD) shows geographic variation. Since no true population surveys are available, at least some of this variation could be due to selection bias. The usually reported prevalence is less than 1% among patients from the Western countries and the Middle East while this frequency becomes 10% or higher in the Far East with reports of around 25% from Japan. As in Crohn's disease (CD), gastrointestinal Behçet's disease (GIBD) is seen most commonly in the ileocecal area. Lesions in the esophagus and stomach are distinctly rare. It is quite difficult to differentiate GIBD from CD disease unless other stigmata of either condition are present. The rarity of rectal involvement and the absence of granulomas in GIBD can on occasion be helpful. On the other hand, the presence of these two features in CD (∼10% for rectal disease and 10-15% for granuloma formation) is not frequent either, reducing their usefulness in differential diagnosis. Thus far, outcome perforation is more common in GIBD (25-50%) than in Crohn's (∼2%). Management of GIBD is very similar to what we do in CD. Surgical treatment is reserved for complications like perforation, bleeding, obstruction, and stubborn fistula formation. Since relapses are frequent even under medical treatment, surgical resection should be conservative.

Original languageEnglish
Title of host publicationBehçet's Syndrome
PublisherSpringer New York
Pages165-188
Number of pages24
ISBN (Print)9781441956408
DOIs
Publication statusPublished - 2010 Dec 1

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Gastrointestinal Diseases
Crohn Disease
Granuloma
Rectal Diseases
Christianity
Middle East
Far East
Selection Bias
Esophagus
Fistula
Stomach
Japan
Differential Diagnosis
Hemorrhage
Recurrence
Therapeutics
Population

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Cheon, J., Çelik, A. F., & Kim, W. H. (2010). Behçet's disease: Gastrointestinal involvement. In Behçet's Syndrome (pp. 165-188). Springer New York. https://doi.org/10.1007/978-1-4419-5641-5_10
Cheon, JaeHee ; Çelik, Aykut Ferhat ; Kim, Won Ho. / Behçet's disease : Gastrointestinal involvement. Behçet's Syndrome. Springer New York, 2010. pp. 165-188
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Cheon, J, Çelik, AF & Kim, WH 2010, Behçet's disease: Gastrointestinal involvement. in Behçet's Syndrome. Springer New York, pp. 165-188. https://doi.org/10.1007/978-1-4419-5641-5_10

Behçet's disease : Gastrointestinal involvement. / Cheon, JaeHee; Çelik, Aykut Ferhat; Kim, Won Ho.

Behçet's Syndrome. Springer New York, 2010. p. 165-188.

Research output: Chapter in Book/Report/Conference proceedingChapter

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Cheon J, Çelik AF, Kim WH. Behçet's disease: Gastrointestinal involvement. In Behçet's Syndrome. Springer New York. 2010. p. 165-188 https://doi.org/10.1007/978-1-4419-5641-5_10