A new benzimidazole-based receptor was developed with potential functional groups for excited state proton transfer (ESPT) through keto-enol tautomerism. The enol form of the receptor selectively recognizes Zn 2+, allowing it to be used as a ratiometric fluorescence sensor in DMSO/CH 3CN (1:9, v/v). The binding event triggers a blue-shifted band through the modulation of charge transfer transitions. The sensor is applicable for recognizing Zn 2+ in the cytoplasm of Saccharomyces cerevisiae.
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry