A direct one-pot access to diarylmethylazides, versatile intermediates, from commercially available starting materials was enabled via three-component coupling of aldehydes, arenes, and TMSN3 in the presence of a catalytic amount of BF3·OEt2.
Bibliographical noteFunding Information:
We thank the National Research Foundation of Korea ( NRF-2018R1A6A1A03023718 and NRF-2020R1A2C2005961 ) for generous financial support.
© 2021 Elsevier Ltd
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry