Bi nanowire-based thermal biosensor for the detection of salivary cortisol using the Thomson effect

Seunghyun Lee, Jung Hyun Lee, Mingin Kim, Jeongmin Kim, Min Jung Song, Hyo Il Jung, Wooyoung Lee

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We present a study of a thermal biosensor based on bismuth nanowire that is fabricated for the detection of the human stress hormone cortisol using the Thomson effect. The Bi nanowire was grown using the On-Film Formation of Nanowires (OFF-ON) method. The thermal device was fabricated using photolithography, and the sensing area was modified with immobilized anti-cortisol antibodies conjugated with protein G for the detection of cortisol. The voltages were measured with two probe tips during surface modification to investigate the biochemical reactions in the fabricated thermal biosensor. The Bi nanowire-based thermal biosensor exhibited low detection limit and good selectivity for the detection of cortisol.

Original languageEnglish
Article number143114
JournalApplied Physics Letters
Volume103
Issue number14
DOIs
Publication statusPublished - 2013 Oct 21

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thermoelectricity
bioinstrumentation
nanowires
hormones
photolithography
antibodies
bismuth
selectivity
proteins
probes
electric potential

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy (miscellaneous)

Cite this

Lee, Seunghyun ; Hyun Lee, Jung ; Kim, Mingin ; Kim, Jeongmin ; Song, Min Jung ; Jung, Hyo Il ; Lee, Wooyoung. / Bi nanowire-based thermal biosensor for the detection of salivary cortisol using the Thomson effect. In: Applied Physics Letters. 2013 ; Vol. 103, No. 14.
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Bi nanowire-based thermal biosensor for the detection of salivary cortisol using the Thomson effect. / Lee, Seunghyun; Hyun Lee, Jung; Kim, Mingin; Kim, Jeongmin; Song, Min Jung; Jung, Hyo Il; Lee, Wooyoung.

In: Applied Physics Letters, Vol. 103, No. 14, 143114, 21.10.2013.

Research output: Contribution to journalArticle

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