Abstract
Segmental neurofibromatosis, a subtype of neurofibromatosis type 1, is characterized by neurofibromas and/or café-au-lait spots limited to an area or segment of the body. Checkerboard pattern is a rare type of cutaneous mosaic manifestation, characterized by squares or broad ribbons of affected skin with sharp demarcation at the midline. Herein, we report the case of a patient with bilateral segmental neurofibromatosis with lentiginosis showing a checkerboard pattern. Our patient had multiple hyperpigmented macules on her entire body in a checkerboard pattern since birth. Several cafe-au-lait patches were observed on the left buttock and right axilla. A neurofibroma was incidentally found beneath the cafe-au-lait patch by histological examination, which showed ill-defined spindle cells with elongated nuclei at the deep dermis that stained positive for S-100. Based on the clinical presentation and histopathologic results, the patient was diagnosed with bilateral segmental neurofibromatosis with lentiginosis showing a checkerboard pattern. (Korean J Dermatol 2019;57(6):328∼331).
| Original language | English |
|---|---|
| Pages (from-to) | 328-331 |
| Number of pages | 4 |
| Journal | Korean Journal of Dermatology |
| Volume | 57 |
| Issue number | 6 |
| Publication status | Published - 2019 Jul |
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All Science Journal Classification (ASJC) codes
- Dermatology
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Bilateral segmental neurofibromatosis with lentiginosis showing a checkerboard pattern. / Park, Seh Hyun; Lee, Si Hyung; Kim, Soo Chan.
In: Korean Journal of Dermatology, Vol. 57, No. 6, 07.2019, p. 328-331.Research output: Contribution to journal › Article
TY - JOUR
T1 - Bilateral segmental neurofibromatosis with lentiginosis showing a checkerboard pattern
AU - Park, Seh Hyun
AU - Lee, Si Hyung
AU - Kim, Soo Chan
PY - 2019/7
Y1 - 2019/7
N2 - Segmental neurofibromatosis, a subtype of neurofibromatosis type 1, is characterized by neurofibromas and/or café-au-lait spots limited to an area or segment of the body. Checkerboard pattern is a rare type of cutaneous mosaic manifestation, characterized by squares or broad ribbons of affected skin with sharp demarcation at the midline. Herein, we report the case of a patient with bilateral segmental neurofibromatosis with lentiginosis showing a checkerboard pattern. Our patient had multiple hyperpigmented macules on her entire body in a checkerboard pattern since birth. Several cafe-au-lait patches were observed on the left buttock and right axilla. A neurofibroma was incidentally found beneath the cafe-au-lait patch by histological examination, which showed ill-defined spindle cells with elongated nuclei at the deep dermis that stained positive for S-100. Based on the clinical presentation and histopathologic results, the patient was diagnosed with bilateral segmental neurofibromatosis with lentiginosis showing a checkerboard pattern. (Korean J Dermatol 2019;57(6):328∼331).
AB - Segmental neurofibromatosis, a subtype of neurofibromatosis type 1, is characterized by neurofibromas and/or café-au-lait spots limited to an area or segment of the body. Checkerboard pattern is a rare type of cutaneous mosaic manifestation, characterized by squares or broad ribbons of affected skin with sharp demarcation at the midline. Herein, we report the case of a patient with bilateral segmental neurofibromatosis with lentiginosis showing a checkerboard pattern. Our patient had multiple hyperpigmented macules on her entire body in a checkerboard pattern since birth. Several cafe-au-lait patches were observed on the left buttock and right axilla. A neurofibroma was incidentally found beneath the cafe-au-lait patch by histological examination, which showed ill-defined spindle cells with elongated nuclei at the deep dermis that stained positive for S-100. Based on the clinical presentation and histopathologic results, the patient was diagnosed with bilateral segmental neurofibromatosis with lentiginosis showing a checkerboard pattern. (Korean J Dermatol 2019;57(6):328∼331).
UR - http://www.scopus.com/inward/record.url?scp=85071909412&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85071909412&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85071909412
VL - 57
SP - 328
EP - 331
JO - Korean Journal of Dermatology
JF - Korean Journal of Dermatology
SN - 0494-4739
IS - 6
ER -