Biochemical characterization of the TEM-107 extended-spectrum β-lactamase in a Klebsiella pneumoniae isolate from South Korea

Kyungwon Lee, Jong Hwa Yum, Dongeun Yong, Seok Hoon Jeong, Gian Maria Rossolini, Jean Denis Docquier, Yunsop Chong

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

The TEM-107 extended-spectrum β-lactamase detected in a Klebsiella pneumoniae clinical isolate had a Gly238Ser substitution compared to the TEM-43 β-lactamase. The MIC of ceftazidime was higher (64 μg/ml) than that of cefotaxime (2 μg/ml) for the isolate. Clavulanic acid reduced the MIC of ceftazidime 64-fold.

Original languageEnglish
Pages (from-to)5930-5932
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume55
Issue number12
DOIs
Publication statusPublished - 2011 Dec

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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