Biocompatibility and charge injection property of iridium film formed by ion beam assisted deposition

In Seop Lee, Chung Nam Whang, Jongchul Park, Dong Hee Lee, Won Sun Seo

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Iridium thin film formed by electron-beam evaporation with simultaneous bombardment of Ar ion beam was evaluated for a stimulating neural electrode. The electrochemical behavior of as-deposited Ir film on Ni-Ti sample was almost identical to bulk Ir by producing much higher open-circuit corrosion potential and much lower anodic current density than the uncoated Ni-Ti in both 1N sulfuric acid and saline solution. The charge injection capability of Ir film was compared with that of Pt electrode currently used mostly as a stimulating neural electrode. The charge density of Pt was small and unchanged with increasing number of activating cycles in 0.1M H2SO4, whilst the Ir film continuously produced increases in charge density. The charge injection density of Ir film in physiological solution was higher for the more activated sample under the identical stimulating condition. Attachment and proliferation with PC12 cells on Ir-coated CP Ti without applying electrical stimulation was similar to the polished CP Ti. A network of neurons and extending axons were formed on Ir film.

Original languageEnglish
Pages (from-to)2225-2231
Number of pages7
JournalBiomaterials
Volume24
Issue number13
DOIs
Publication statusPublished - 2003 Jan 1

Fingerprint

Ion beam assisted deposition
Iridium
Charge injection
Biocompatibility
Electrodes
Ions
Injections
Charge density
Corrosion
PC12 Cells
Sodium Chloride
Electric Stimulation
Axons
Electrons
Neurons
Sulfuric acid
Ion beams
Electron beams
Evaporation
Current density

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Ceramics and Composites
  • Biophysics
  • Biomaterials
  • Mechanics of Materials

Cite this

Lee, In Seop ; Whang, Chung Nam ; Park, Jongchul ; Lee, Dong Hee ; Seo, Won Sun. / Biocompatibility and charge injection property of iridium film formed by ion beam assisted deposition. In: Biomaterials. 2003 ; Vol. 24, No. 13. pp. 2225-2231.
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Biocompatibility and charge injection property of iridium film formed by ion beam assisted deposition. / Lee, In Seop; Whang, Chung Nam; Park, Jongchul; Lee, Dong Hee; Seo, Won Sun.

In: Biomaterials, Vol. 24, No. 13, 01.01.2003, p. 2225-2231.

Research output: Contribution to journalArticle

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AB - Iridium thin film formed by electron-beam evaporation with simultaneous bombardment of Ar ion beam was evaluated for a stimulating neural electrode. The electrochemical behavior of as-deposited Ir film on Ni-Ti sample was almost identical to bulk Ir by producing much higher open-circuit corrosion potential and much lower anodic current density than the uncoated Ni-Ti in both 1N sulfuric acid and saline solution. The charge injection capability of Ir film was compared with that of Pt electrode currently used mostly as a stimulating neural electrode. The charge density of Pt was small and unchanged with increasing number of activating cycles in 0.1M H2SO4, whilst the Ir film continuously produced increases in charge density. The charge injection density of Ir film in physiological solution was higher for the more activated sample under the identical stimulating condition. Attachment and proliferation with PC12 cells on Ir-coated CP Ti without applying electrical stimulation was similar to the polished CP Ti. A network of neurons and extending axons were formed on Ir film.

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