Biofilm formation and genotyping of Candida haemulonii, Candida pseudohaemulonii, and a proposed new species (Candida auris) isolates from Korea

Bong Joon Oh, Jong Hee Shin, Mi Na Kim, Heungsup Sung, Kyungwon Lee, Min Young Joo, Myung Geun Shin, Soon Pal Suh, Dong Wook Ryang

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

Emergence of Candida haemulonii and closely related species at five Korean hospitals has been recently described. We examined biofilm formation by these isolates and assessed their genotypic relatedness by pulsed-field gel electrophoresis (PFGE). This study is the first to show that all bloodstream isolates of Candida pseudohaemulonii can form significant biofilms in glucose-containing medium. PFGE of NotI-digested genomic DNA revealed that C. pseudohaemulonii isolates recovered from seven patients in two hospitals shared five patterns, and that 15 isolates of a proposed new species (Candida auris) obtained from patients at three hospitals shared seven patterns, suggesting that some of these isolates may be related to clonal transmission.

Original languageEnglish
Pages (from-to)98-102
Number of pages5
JournalMedical mycology
Volume49
Issue number1
DOIs
Publication statusPublished - 2010 Jan 1

All Science Journal Classification (ASJC) codes

  • Infectious Diseases

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