In the construction of dental restorative polymer composite materials, surface priming on mineral fillers is essential to improve the mechanical performance of the composites. Here we present bioinspired catechol-functionalized primers for a tougher dental resin composite containing glass fillers. The catecholic primers with different polymerizable end groups were designed and then coated on glass surfaces using a simple drop-casting or dip-coating process. The surface binding ability and possible cross-linking (coupling or chemical bridging between the glass substrate and the dental resin) of the catecholic bifunctional primers were evaluated using atomic force microscopy, contact angle measurements, and the knife shear bonding test and compared to a state-of-the-art silane-based coupling agent. Various mechanical tests including shrinkage and compression tests of the dental resin composites were also conducted. Compression tests of the composites containing the catecholic primed fillers exhibited enhanced mechanical properties, owing to the bidentate hydrogen bonding of catechol moieties to the oxide mineral surface. Furthermore, the superior biocompatibility of the primed surface was confirmed via cell attachment assay, thus providing applicability of catecholic primers for practical dental and biomedical applications.
Bibliographical noteFunding Information:
The authors gratefully acknowledge support from the Office of Naval Research N000141310867. This work was also supported by the National Research Foundation of Korea (NRF) grant (NRF-2017R1A2B3012148). The authors wish to thank Osaka Organic Chemical Industry Ltd (Japan) for providing the triethylsilane-protected eugenol acrylate and methacrylate. The authors also wish to thank Stephanie Doan and Komal Ahluwalia for their contributions to the pilot experiments via the Research Mentorship Program at the UC Santa Barbara.
All Science Journal Classification (ASJC) codes
- Materials Science(all)