Biological efficacy of two mineral trioxide aggregate (Mta)-based materials in a canine model of pulpotomy

Myeongyeon Lee; Chung Min Kang; Je Seon Song; Yoo Seok Shin; Seungh Ye Kim; Seong Oh Kim; Hyung Jun Choi

doi:10.4012/dmj.2016-121

Biological efficacy of two mineral trioxide aggregate (Mta)-based materials in a canine model of pulpotomy

Myeongyeon Lee, Chung Min Kang, Je Seon Song, Yoo Seok Shin, Seungh Ye Kim, Seong Oh Kim, Hyung Jun Choi

Department of Pediatric Dentistry

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

The aim of this study was to compare the biocompatibility of Endocem Zr® and ProRoot MTA® by histopathologic analysis in a canine model of pulpotomy. This study utilized 39 teeth of two beagle dogs. The exposed pulp tissues were treated by pulpotomy using ProRoot MTA (n=19) or Endocem Zr (n=20). After 8 weeks, the teeth were extracted and processed with hematoxylin-eosin staining for histologic evaluation. Most of the specimens in both groups developed a calcific barrier at the pulp amputation site and formed an odontoblast layer. However, some of the Endocem Zr specimens showed less calcific barrier formation with a greater inflammatory response and less odontoblast layer formation when compared with the ProRoot MTA specimens. ProRoot MTA and Endocem Zr specimens developed a calcific barrier; however, ProRoot MTA was more biocompatible than Endocem Zr.

Original language	English
Article number	dmj/2016-121
Pages (from-to)	41-47
Number of pages	7
Journal	Dental Materials Journal
Volume	36
Issue number	1
DOIs	https://doi.org/10.4012/dmj.2016-121
Publication status	Published - 2017

Bibliographical note

Funding Information:
This study was supported by the Yonsei University College of Dentistry Fund (6-2014-0083). The authors deny any conflicts of interest related to this study.

All Science Journal Classification (ASJC) codes

Ceramics and Composites
Dentistry(all)

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title = "Biological efficacy of two mineral trioxide aggregate (Mta)-based materials in a canine model of pulpotomy",

abstract = "The aim of this study was to compare the biocompatibility of Endocem Zr{\textregistered} and ProRoot MTA{\textregistered} by histopathologic analysis in a canine model of pulpotomy. This study utilized 39 teeth of two beagle dogs. The exposed pulp tissues were treated by pulpotomy using ProRoot MTA (n=19) or Endocem Zr (n=20). After 8 weeks, the teeth were extracted and processed with hematoxylin-eosin staining for histologic evaluation. Most of the specimens in both groups developed a calcific barrier at the pulp amputation site and formed an odontoblast layer. However, some of the Endocem Zr specimens showed less calcific barrier formation with a greater inflammatory response and less odontoblast layer formation when compared with the ProRoot MTA specimens. ProRoot MTA and Endocem Zr specimens developed a calcific barrier; however, ProRoot MTA was more biocompatible than Endocem Zr.",

author = "Myeongyeon Lee and Kang, {Chung Min} and Song, {Je Seon} and Shin, {Yoo Seok} and Kim, {Seungh Ye} and Kim, {Seong Oh} and Choi, {Hyung Jun}",

note = "Funding Information: This study was supported by the Yonsei University College of Dentistry Fund (6-2014-0083). The authors deny any conflicts of interest related to this study.",

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AU - Lee, Myeongyeon

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AU - Song, Je Seon

AU - Shin, Yoo Seok

AU - Kim, Seungh Ye

AU - Kim, Seong Oh

AU - Choi, Hyung Jun

N1 - Funding Information: This study was supported by the Yonsei University College of Dentistry Fund (6-2014-0083). The authors deny any conflicts of interest related to this study.

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