Biological safety evaluation of polyketones as biomaterials

Mi Hee Lee, Dae Hyung Lee, Hyun Sook Baek, Byeong Ju Kwon, Min Ah Koo, Min Sung Kim, Gyeung Mi Seon, Jongchul Park

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Biomaterials for clinical applications such as medical and implant devices require evaluation to determine their biocompatibility. This study aimed to evaluate the initial biological safety of polyketone (PK) polymers, which have potential use as biomaterials. It presents results from cytotoxicity and genotoxicity assays and tests determining the levels of skin irritation, sensitization, and acute systemic toxicity caused by PK. The PK polymers showed no cytotoxicity, genotoxicity, allergenicity, irritancy, and systemic toxicity. These results indicate that the PK polymers are potentially biological safe and could be used to replace non-degradable polymeric biomaterials.

Original languageEnglish
Pages (from-to)225-231
Number of pages7
JournalPolymer (Korea)
Volume40
Issue number2
DOIs
Publication statusPublished - 2016 Mar 1

Fingerprint

Biocompatible Materials
Biomaterials
Polymers
Cytotoxicity
Toxicity
Biocompatibility
Assays
Skin

All Science Journal Classification (ASJC) codes

  • Chemical Engineering(all)
  • Polymers and Plastics
  • Materials Chemistry

Cite this

Lee, M. H., Lee, D. H., Baek, H. S., Kwon, B. J., Koo, M. A., Kim, M. S., ... Park, J. (2016). Biological safety evaluation of polyketones as biomaterials. Polymer (Korea), 40(2), 225-231. https://doi.org/10.7317/pk.2016.40.2.225
Lee, Mi Hee ; Lee, Dae Hyung ; Baek, Hyun Sook ; Kwon, Byeong Ju ; Koo, Min Ah ; Kim, Min Sung ; Seon, Gyeung Mi ; Park, Jongchul. / Biological safety evaluation of polyketones as biomaterials. In: Polymer (Korea). 2016 ; Vol. 40, No. 2. pp. 225-231.
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Lee, MH, Lee, DH, Baek, HS, Kwon, BJ, Koo, MA, Kim, MS, Seon, GM & Park, J 2016, 'Biological safety evaluation of polyketones as biomaterials', Polymer (Korea), vol. 40, no. 2, pp. 225-231. https://doi.org/10.7317/pk.2016.40.2.225

Biological safety evaluation of polyketones as biomaterials. / Lee, Mi Hee; Lee, Dae Hyung; Baek, Hyun Sook; Kwon, Byeong Ju; Koo, Min Ah; Kim, Min Sung; Seon, Gyeung Mi; Park, Jongchul.

In: Polymer (Korea), Vol. 40, No. 2, 01.03.2016, p. 225-231.

Research output: Contribution to journalArticle

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AU - Seon, Gyeung Mi

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Lee MH, Lee DH, Baek HS, Kwon BJ, Koo MA, Kim MS et al. Biological safety evaluation of polyketones as biomaterials. Polymer (Korea). 2016 Mar 1;40(2):225-231. https://doi.org/10.7317/pk.2016.40.2.225