Biomechanical tests of osteoporotic vertebral trabecular bone using finite element analysis based on micro-CT

Dae Gon Woo, Tae Woo Lee, Chang Yong Ko, Han Sung Kim, Ye Yeon Won

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Osteoporosis results in high fracture risks of vertebral bone. A considerable amount of work has been done to investigate the biomechanical characteristics of osteoporotic vertebral trabecular bone. Previous researchers studied the elastic characteristics using a micro-finite element (micro-FE) model, used to analyze realistic trabecular architectures in full detail, based on micro-computed tomography (μCT). Since osteoporotic compression fracture is closely associated with the mechanical characteristics of the vertebral trabecular bone and there were few micro-FE models to account for all of the elastic and plastic characteristics in vertebral trabecular bone, this study analyzed the effect of voxel resolution on the plastic as well as the elastic characteristics of three-dimensional (3D) osteoporotic lumbar trabecular bone models. Also, we evaluated the effect of specimen size on this problem. It has been reported that a cubic specimen with side length 6.5mm was suggested as standard specimens for the experimental test of trabecular bone. Current study examined whether or not the effect of the specimen geometry on the experimental test may be also applied to the simulated compression test of trabecular bone specimens. The experimental test employing the rapid prototyping (RP) technique and INSTRON test machine is performed to indirectly validate the results of the simulated compression test by micro-FE analysis. The review finished with the verification about the effects of the simulated compression test.

Original languageEnglish
Title of host publicationICBPE 2006 - Proceedings of the 2006 International Conference on Biomedical and Pharmaceutical Engineering
Pages231-236
Number of pages6
DOIs
Publication statusPublished - 2006
EventICBPE 2006 - 2006 International Conference on Biomedical and Pharmaceutical Engineering - Singapore, Singapore
Duration: 2006 Dec 112006 Dec 14

Publication series

NameICBPE 2006 - Proceedings of the 2006 International Conference on Biomedical and Pharmaceutical Engineering

Other

OtherICBPE 2006 - 2006 International Conference on Biomedical and Pharmaceutical Engineering
CountrySingapore
CitySingapore
Period06/12/1106/12/14

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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