Black Phosphorus Nanoparticle Labels for Immunoassays via Hydrogen Evolution Reaction Mediation

Carmen C. Mayorga-Martinez; Naziah Mohamad Latiff; Alex Yong Sheng Eng; Zdeněk Sofer; Martin Pumera

doi:10.1021/acs.analchem.6b02422

Black Phosphorus Nanoparticle Labels for Immunoassays via Hydrogen Evolution Reaction Mediation

Carmen C. Mayorga-Martinez, Naziah Mohamad Latiff, Alex Yong Sheng Eng, Zdeněk Sofer, Martin Pumera

Department of Chemical and Biomolecular Engineering

Research output: Contribution to journal › Article › peer-review

96 Citations (Scopus)

Abstract

Black phosphorus is an emerging layered material. Its nanoparticles show an increased bandgap when compared to bulk materials and they are typically fabricated by ultrasonication of macroscopic black phosphorus crystals. Here we fabricate black phosphorus nanoparticles (BP NPs) by solution based electrochemical exfoliation with bipolar electrodes, which induces opposite potentials on the opposite ends of black phosphorus macroparticles thereby leading to its decomposition into nanoparticles. BP NPs have enhanced catalytic effect on the hydrogen evolution reaction (HER) relative to black phosphorus macroparticles. We utilize black phosphorus nanoparticles as electrocatalytic tags in a competitive immunoassay for rabbit immunoglobulin G (IgG) detection. The detection signal is produced via nanoimpacts of the BP NPs followed by HER catalysis.

Original language	English
Pages (from-to)	10074-10079
Number of pages	6
Journal	Analytical Chemistry
Volume	88
Issue number	20
DOIs	https://doi.org/10.1021/acs.analchem.6b02422
Publication status	Published - 2016 Oct 18

Bibliographical note

Funding Information:
M.P. was supported by Tier 2 grant (Grant MOE2013-T2-1-056; ARC 35/13) from the Ministry of Education, Singapore. Z.S. was supported by the Czech Science Foundation (GACR Grant No. 15-09001S).

Publisher Copyright:
© 2016 American Chemical Society.

All Science Journal Classification (ASJC) codes

Analytical Chemistry

Access to Document

10.1021/acs.analchem.6b02422

Cite this

@article{800be6938ce14f0b95a3558ca38347ae,

title = "Black Phosphorus Nanoparticle Labels for Immunoassays via Hydrogen Evolution Reaction Mediation",

abstract = "Black phosphorus is an emerging layered material. Its nanoparticles show an increased bandgap when compared to bulk materials and they are typically fabricated by ultrasonication of macroscopic black phosphorus crystals. Here we fabricate black phosphorus nanoparticles (BP NPs) by solution based electrochemical exfoliation with bipolar electrodes, which induces opposite potentials on the opposite ends of black phosphorus macroparticles thereby leading to its decomposition into nanoparticles. BP NPs have enhanced catalytic effect on the hydrogen evolution reaction (HER) relative to black phosphorus macroparticles. We utilize black phosphorus nanoparticles as electrocatalytic tags in a competitive immunoassay for rabbit immunoglobulin G (IgG) detection. The detection signal is produced via nanoimpacts of the BP NPs followed by HER catalysis.",

author = "Mayorga-Martinez, {Carmen C.} and {Mohamad Latiff}, Naziah and Eng, {Alex Yong Sheng} and Zden{\v e}k Sofer and Martin Pumera",

note = "Funding Information: M.P. was supported by Tier 2 grant (Grant MOE2013-T2-1-056; ARC 35/13) from the Ministry of Education, Singapore. Z.S. was supported by the Czech Science Foundation (GACR Grant No. 15-09001S). Publisher Copyright: {\textcopyright} 2016 American Chemical Society.",

year = "2016",

month = oct,

day = "18",

doi = "10.1021/acs.analchem.6b02422",

language = "English",

volume = "88",

pages = "10074--10079",

journal = "Analytical Chemistry",

issn = "0003-2700",

number = "20",

}

TY - JOUR

T1 - Black Phosphorus Nanoparticle Labels for Immunoassays via Hydrogen Evolution Reaction Mediation

AU - Mayorga-Martinez, Carmen C.

AU - Mohamad Latiff, Naziah

AU - Eng, Alex Yong Sheng

AU - Sofer, Zdeněk

AU - Pumera, Martin

N1 - Funding Information: M.P. was supported by Tier 2 grant (Grant MOE2013-T2-1-056; ARC 35/13) from the Ministry of Education, Singapore. Z.S. was supported by the Czech Science Foundation (GACR Grant No. 15-09001S). Publisher Copyright: © 2016 American Chemical Society.

PY - 2016/10/18

Y1 - 2016/10/18

N2 - Black phosphorus is an emerging layered material. Its nanoparticles show an increased bandgap when compared to bulk materials and they are typically fabricated by ultrasonication of macroscopic black phosphorus crystals. Here we fabricate black phosphorus nanoparticles (BP NPs) by solution based electrochemical exfoliation with bipolar electrodes, which induces opposite potentials on the opposite ends of black phosphorus macroparticles thereby leading to its decomposition into nanoparticles. BP NPs have enhanced catalytic effect on the hydrogen evolution reaction (HER) relative to black phosphorus macroparticles. We utilize black phosphorus nanoparticles as electrocatalytic tags in a competitive immunoassay for rabbit immunoglobulin G (IgG) detection. The detection signal is produced via nanoimpacts of the BP NPs followed by HER catalysis.

AB - Black phosphorus is an emerging layered material. Its nanoparticles show an increased bandgap when compared to bulk materials and they are typically fabricated by ultrasonication of macroscopic black phosphorus crystals. Here we fabricate black phosphorus nanoparticles (BP NPs) by solution based electrochemical exfoliation with bipolar electrodes, which induces opposite potentials on the opposite ends of black phosphorus macroparticles thereby leading to its decomposition into nanoparticles. BP NPs have enhanced catalytic effect on the hydrogen evolution reaction (HER) relative to black phosphorus macroparticles. We utilize black phosphorus nanoparticles as electrocatalytic tags in a competitive immunoassay for rabbit immunoglobulin G (IgG) detection. The detection signal is produced via nanoimpacts of the BP NPs followed by HER catalysis.

UR - http://www.scopus.com/inward/record.url?scp=84991744824&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84991744824&partnerID=8YFLogxK

U2 - 10.1021/acs.analchem.6b02422

DO - 10.1021/acs.analchem.6b02422

M3 - Article

AN - SCOPUS:84991744824

VL - 88

SP - 10074

EP - 10079

JO - Analytical Chemistry

JF - Analytical Chemistry

SN - 0003-2700

IS - 20

ER -

Black Phosphorus Nanoparticle Labels for Immunoassays via Hydrogen Evolution Reaction Mediation

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this