We propose a blind adaptive post-processing method to reduce nonlinear distortion in multiband radio over fiber (RoF) transmission. Mitigating nonlinear distortion has been a critical challenge to enhance signal quality in RoF system due to analog optical transmission. To keep up with explosive increase in number of mobiles and their data capacity demands, remote antenna unit (RAU) has to be widely and densely distributed with RoF system. Consequently, RAU should be simple and compensation should be fully processed in central office (CO). In optical uplink transmission of RoF system, post-processing of distortion mitigation will be effective. In this paper, we propose post compensation structure constructed by means of Hammerstein equalizer without inserting preamble. Specifically, Hammerstein equalizer, which is separated into linear and nonlinear parts, was used to compensate both linear and nonlinear distortion of RoF system. The filter coefficients were updated adaptively by using LMS algorithm to adjust variable channel environments. In our experiment, multiband OFDM signal, which is LTE standard according to 3GPP, was optically transmitted through RoF channel. Experimental demonstration for the improvement of EVM performance with proposed post-processing was verified.