Body composition and its association with cardiometabolic risk factors in the elderly: A focus on sarcopenic obesity

Ji Youn Chung, Hee Taik Kang, Duk Chul Lee, Hye Ree Lee, Yong Jae Lee

Research output: Contribution to journalArticle

105 Citations (Scopus)

Abstract

Important changes in body composition with aging are a progressive loss of muscle mass and increase of fat mass. Despite their enormous clinical importance, body composition changes such as sarcopenic obesity in the elderly are under-recognized. This study aimed to examine the relationship of body composition with a wide variety of cardiometabolic risk factors among 2943 subjects (1250 men and 1693 women) aged 60 years or older from Korean National Health Examination and Nutrition Survey (KNHANES). Sarcopenia was defined as an appendicular skeletal muscle mass (ASM) divided by weight (%) of <1 SD below the sex-specific mean for young adults. Obesity was defined as a body mass index (BMI) ≥25kg/m2. Body composition was categorized into four non-overlapping groups: the sarcopenic obese, sarcopenic nonobese, nonsarcopenic obese, and nonsarcopenic nonobese groups. A wide variety of cardiometabolic risk factors, including blood pressure (BP), glucose tolerance indices, lipid profiles, inflammatory markers, and vitamin D level, were compared according to body composition group. The prevalence of sarcopenic obesity was 18.4% in men and 25.8% in women. In both sexes, the prevalence of vitamin D deficiency and metabolic syndrome was highly prevalent in the sarcopenic obese group. Serum insulin level, homeostasis model assessment of insulin resistance (HOMA-IR), triglyceride levels, and ferritin levels were the highest in the sarcopenic obese group in both men and women, whereas HDL-cholesterol and 25-hydroxyvitamin D (25(OH)D) levels were the lowest in the sarcopenic obese group. The sarcopenic obese group was more closely associated with insulin resistance, metabolic syndrome, and cardiovascular disease (CVD) risk factors than any other group in this elderly population.

Original languageEnglish
Pages (from-to)270-278
Number of pages9
JournalArchives of Gerontology and Geriatrics
Volume56
Issue number1
DOIs
Publication statusPublished - 2013 Jan 1

Fingerprint

Body Composition
Obesity
Group
Insulin Resistance
Sarcopenia
Vitamin D Deficiency
Nutrition Surveys
Metabolic Diseases
Ferritins
Vitamin D
HDL Cholesterol
Blood Glucose
Young Adult
Skeletal Muscle
Triglycerides
Body Mass Index
Homeostasis
Cardiovascular Diseases
Fats
Insulin

All Science Journal Classification (ASJC) codes

  • Health(social science)
  • Ageing
  • Gerontology
  • Geriatrics and Gerontology

Cite this

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title = "Body composition and its association with cardiometabolic risk factors in the elderly: A focus on sarcopenic obesity",
abstract = "Important changes in body composition with aging are a progressive loss of muscle mass and increase of fat mass. Despite their enormous clinical importance, body composition changes such as sarcopenic obesity in the elderly are under-recognized. This study aimed to examine the relationship of body composition with a wide variety of cardiometabolic risk factors among 2943 subjects (1250 men and 1693 women) aged 60 years or older from Korean National Health Examination and Nutrition Survey (KNHANES). Sarcopenia was defined as an appendicular skeletal muscle mass (ASM) divided by weight ({\%}) of <1 SD below the sex-specific mean for young adults. Obesity was defined as a body mass index (BMI) ≥25kg/m2. Body composition was categorized into four non-overlapping groups: the sarcopenic obese, sarcopenic nonobese, nonsarcopenic obese, and nonsarcopenic nonobese groups. A wide variety of cardiometabolic risk factors, including blood pressure (BP), glucose tolerance indices, lipid profiles, inflammatory markers, and vitamin D level, were compared according to body composition group. The prevalence of sarcopenic obesity was 18.4{\%} in men and 25.8{\%} in women. In both sexes, the prevalence of vitamin D deficiency and metabolic syndrome was highly prevalent in the sarcopenic obese group. Serum insulin level, homeostasis model assessment of insulin resistance (HOMA-IR), triglyceride levels, and ferritin levels were the highest in the sarcopenic obese group in both men and women, whereas HDL-cholesterol and 25-hydroxyvitamin D (25(OH)D) levels were the lowest in the sarcopenic obese group. The sarcopenic obese group was more closely associated with insulin resistance, metabolic syndrome, and cardiovascular disease (CVD) risk factors than any other group in this elderly population.",
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Body composition and its association with cardiometabolic risk factors in the elderly : A focus on sarcopenic obesity. / Chung, Ji Youn; Kang, Hee Taik; Lee, Duk Chul; Lee, Hye Ree; Lee, Yong Jae.

In: Archives of Gerontology and Geriatrics, Vol. 56, No. 1, 01.01.2013, p. 270-278.

Research output: Contribution to journalArticle

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