Body mass index is associated with hypercholesterolemia following thyroid hormone withdrawal in thyroidectomized patients

Dong Yeob Shin, Kwang Joon Kim, Yongin Cho, Kyeong Hye Park, Sena Hwang, Woong Youn Chung, Eun Jig Lee

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Thyroid hormone withdrawal (THW) for postoperative radioiodine adjuvant therapy or diagnostic radioiodine whole body scan in patients with differentiated thyroid cancers results in acute thyroid hormone deficiency and abnormal lipid profiles. To better clarify the clinical pattern of dyslipidemia occurring after THW, we retrospectively analyzed the association between serum total cholesterol level after THW and various clinical factors in a total of 61 patients who underwent total thyroidectomy due to papillary thyroid cancers from January 2010 to March 2012, in Severance Hospital, Seoul, Korea. Preoperative baseline total cholesterol was significantly correlated with post-THW total cholesterol level; however, age, gender, or elevated TSH level after THW itself was not correlated with post-THW total cholesterol level. A significant correlation between preoperative measured BMI and post-THW total cholesterol level was found (r = 0.263, P = 0.041). In multiple logistic analysis, BMI was an independent determining factor of post-THW total cholesterol level (P = 0.012).

Original languageEnglish
Article number649016
JournalInternational Journal of Endocrinology
Volume2014
DOIs
Publication statusPublished - 2014

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Hypercholesterolemia
Thyroid Hormones
Body Mass Index
Cholesterol
Whole Body Imaging
Thyroidectomy
Korea
Dyslipidemias
Thyroid Neoplasms
Lipids
Serum

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Endocrine and Autonomic Systems

Cite this

Shin, Dong Yeob ; Kim, Kwang Joon ; Cho, Yongin ; Park, Kyeong Hye ; Hwang, Sena ; Chung, Woong Youn ; Lee, Eun Jig. / Body mass index is associated with hypercholesterolemia following thyroid hormone withdrawal in thyroidectomized patients. In: International Journal of Endocrinology. 2014 ; Vol. 2014.
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abstract = "Thyroid hormone withdrawal (THW) for postoperative radioiodine adjuvant therapy or diagnostic radioiodine whole body scan in patients with differentiated thyroid cancers results in acute thyroid hormone deficiency and abnormal lipid profiles. To better clarify the clinical pattern of dyslipidemia occurring after THW, we retrospectively analyzed the association between serum total cholesterol level after THW and various clinical factors in a total of 61 patients who underwent total thyroidectomy due to papillary thyroid cancers from January 2010 to March 2012, in Severance Hospital, Seoul, Korea. Preoperative baseline total cholesterol was significantly correlated with post-THW total cholesterol level; however, age, gender, or elevated TSH level after THW itself was not correlated with post-THW total cholesterol level. A significant correlation between preoperative measured BMI and post-THW total cholesterol level was found (r = 0.263, P = 0.041). In multiple logistic analysis, BMI was an independent determining factor of post-THW total cholesterol level (P = 0.012).",
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Body mass index is associated with hypercholesterolemia following thyroid hormone withdrawal in thyroidectomized patients. / Shin, Dong Yeob; Kim, Kwang Joon; Cho, Yongin; Park, Kyeong Hye; Hwang, Sena; Chung, Woong Youn; Lee, Eun Jig.

In: International Journal of Endocrinology, Vol. 2014, 649016, 2014.

Research output: Contribution to journalArticle

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AU - Shin, Dong Yeob

AU - Kim, Kwang Joon

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AU - Hwang, Sena

AU - Chung, Woong Youn

AU - Lee, Eun Jig

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