Brachial-ankle pulse wave velocity for predicting functional outcome in acute stroke

Jinkwon Kim, Tae Jin Song, Eun Hye Kim, Ki Jeong Lee, Hye Sun Lee, Chung Mo Nam, Dongbeom Song, Hyo Suk Nam, Young Dae Kim, Ji Hoe Heo

Research output: Contribution to journalArticle

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Abstract

BACKGROUND AND PURPOSE - : We investigated whether the brachial-ankle pulse wave velocity (baPWV) has prognostic value for predicting functional outcome after acute cerebral infarction and whether the prognostic value differs between stroke subtypes. METHODS - : We included 1091 consecutive patients with first-ever acute cerebral infarction who underwent baPWV measurements. Stroke subtypes were classified using the Trial of Org 10172 in Acute Stroke Treatment classification. Poor functional outcomes were defined as modified Rankin Scale score >2 at 3 months after stroke onset. RESULTS - : We noted that 181 (16.59%) patients had a poor functional outcome. In multivariate logistic regression, patients in the highest tertile of baPWV (>22.25 m/s) were found to be at increased risk for poor functional outcome (adjusted odds ratio, 1.88; 95% confidence interval, 1.06-3.40) compared with those in the lowest tertile (<17.55 m/s). No significant interaction between baPWV and stroke subtype was noted. Receiver operating characteristic curve analysis indicated that the addition of baPWV to the prediction model significantly improved the discrimination ability for poor functional outcome. CONCLUSIONS - : baPWV has an independent prognostic value for predicting functional outcome after acute cerebral infarction. The prognostic value did not differ according to the stroke subtype.

Original languageEnglish
Pages (from-to)2305-2310
Number of pages6
JournalStroke
Volume45
Issue number8
DOIs
Publication statusPublished - 2014 Aug

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Pulse Wave Analysis
Ankle
Arm
Stroke
Cerebral Infarction
ROC Curve
Logistic Models
Odds Ratio
Confidence Intervals

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialised Nursing

Cite this

Kim, Jinkwon ; Song, Tae Jin ; Kim, Eun Hye ; Lee, Ki Jeong ; Lee, Hye Sun ; Nam, Chung Mo ; Song, Dongbeom ; Nam, Hyo Suk ; Kim, Young Dae ; Heo, Ji Hoe. / Brachial-ankle pulse wave velocity for predicting functional outcome in acute stroke. In: Stroke. 2014 ; Vol. 45, No. 8. pp. 2305-2310.
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abstract = "BACKGROUND AND PURPOSE - : We investigated whether the brachial-ankle pulse wave velocity (baPWV) has prognostic value for predicting functional outcome after acute cerebral infarction and whether the prognostic value differs between stroke subtypes. METHODS - : We included 1091 consecutive patients with first-ever acute cerebral infarction who underwent baPWV measurements. Stroke subtypes were classified using the Trial of Org 10172 in Acute Stroke Treatment classification. Poor functional outcomes were defined as modified Rankin Scale score >2 at 3 months after stroke onset. RESULTS - : We noted that 181 (16.59{\%}) patients had a poor functional outcome. In multivariate logistic regression, patients in the highest tertile of baPWV (>22.25 m/s) were found to be at increased risk for poor functional outcome (adjusted odds ratio, 1.88; 95{\%} confidence interval, 1.06-3.40) compared with those in the lowest tertile (<17.55 m/s). No significant interaction between baPWV and stroke subtype was noted. Receiver operating characteristic curve analysis indicated that the addition of baPWV to the prediction model significantly improved the discrimination ability for poor functional outcome. CONCLUSIONS - : baPWV has an independent prognostic value for predicting functional outcome after acute cerebral infarction. The prognostic value did not differ according to the stroke subtype.",
author = "Jinkwon Kim and Song, {Tae Jin} and Kim, {Eun Hye} and Lee, {Ki Jeong} and Lee, {Hye Sun} and Nam, {Chung Mo} and Dongbeom Song and Nam, {Hyo Suk} and Kim, {Young Dae} and Heo, {Ji Hoe}",
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Kim, J, Song, TJ, Kim, EH, Lee, KJ, Lee, HS, Nam, CM, Song, D, Nam, HS, Kim, YD & Heo, JH 2014, 'Brachial-ankle pulse wave velocity for predicting functional outcome in acute stroke', Stroke, vol. 45, no. 8, pp. 2305-2310. https://doi.org/10.1161/STROKEAHA.114.005576

Brachial-ankle pulse wave velocity for predicting functional outcome in acute stroke. / Kim, Jinkwon; Song, Tae Jin; Kim, Eun Hye; Lee, Ki Jeong; Lee, Hye Sun; Nam, Chung Mo; Song, Dongbeom; Nam, Hyo Suk; Kim, Young Dae; Heo, Ji Hoe.

In: Stroke, Vol. 45, No. 8, 08.2014, p. 2305-2310.

Research output: Contribution to journalArticle

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T1 - Brachial-ankle pulse wave velocity for predicting functional outcome in acute stroke

AU - Kim, Jinkwon

AU - Song, Tae Jin

AU - Kim, Eun Hye

AU - Lee, Ki Jeong

AU - Lee, Hye Sun

AU - Nam, Chung Mo

AU - Song, Dongbeom

AU - Nam, Hyo Suk

AU - Kim, Young Dae

AU - Heo, Ji Hoe

PY - 2014/8

Y1 - 2014/8

N2 - BACKGROUND AND PURPOSE - : We investigated whether the brachial-ankle pulse wave velocity (baPWV) has prognostic value for predicting functional outcome after acute cerebral infarction and whether the prognostic value differs between stroke subtypes. METHODS - : We included 1091 consecutive patients with first-ever acute cerebral infarction who underwent baPWV measurements. Stroke subtypes were classified using the Trial of Org 10172 in Acute Stroke Treatment classification. Poor functional outcomes were defined as modified Rankin Scale score >2 at 3 months after stroke onset. RESULTS - : We noted that 181 (16.59%) patients had a poor functional outcome. In multivariate logistic regression, patients in the highest tertile of baPWV (>22.25 m/s) were found to be at increased risk for poor functional outcome (adjusted odds ratio, 1.88; 95% confidence interval, 1.06-3.40) compared with those in the lowest tertile (<17.55 m/s). No significant interaction between baPWV and stroke subtype was noted. Receiver operating characteristic curve analysis indicated that the addition of baPWV to the prediction model significantly improved the discrimination ability for poor functional outcome. CONCLUSIONS - : baPWV has an independent prognostic value for predicting functional outcome after acute cerebral infarction. The prognostic value did not differ according to the stroke subtype.

AB - BACKGROUND AND PURPOSE - : We investigated whether the brachial-ankle pulse wave velocity (baPWV) has prognostic value for predicting functional outcome after acute cerebral infarction and whether the prognostic value differs between stroke subtypes. METHODS - : We included 1091 consecutive patients with first-ever acute cerebral infarction who underwent baPWV measurements. Stroke subtypes were classified using the Trial of Org 10172 in Acute Stroke Treatment classification. Poor functional outcomes were defined as modified Rankin Scale score >2 at 3 months after stroke onset. RESULTS - : We noted that 181 (16.59%) patients had a poor functional outcome. In multivariate logistic regression, patients in the highest tertile of baPWV (>22.25 m/s) were found to be at increased risk for poor functional outcome (adjusted odds ratio, 1.88; 95% confidence interval, 1.06-3.40) compared with those in the lowest tertile (<17.55 m/s). No significant interaction between baPWV and stroke subtype was noted. Receiver operating characteristic curve analysis indicated that the addition of baPWV to the prediction model significantly improved the discrimination ability for poor functional outcome. CONCLUSIONS - : baPWV has an independent prognostic value for predicting functional outcome after acute cerebral infarction. The prognostic value did not differ according to the stroke subtype.

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