Brachial-ankle pulse wave velocity for predicting functional outcome in acute stroke

Jinkwon Kim, Tae Jin Song, Eun Hye Kim, Ki Jeong Lee, Hye Sun Lee, Chung Mo Nam, Dongbeom Song, Hyo Suk Nam, Young Dae Kim, Ji Hoe Heo

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

BACKGROUND AND PURPOSE - : We investigated whether the brachial-ankle pulse wave velocity (baPWV) has prognostic value for predicting functional outcome after acute cerebral infarction and whether the prognostic value differs between stroke subtypes. METHODS - : We included 1091 consecutive patients with first-ever acute cerebral infarction who underwent baPWV measurements. Stroke subtypes were classified using the Trial of Org 10172 in Acute Stroke Treatment classification. Poor functional outcomes were defined as modified Rankin Scale score >2 at 3 months after stroke onset. RESULTS - : We noted that 181 (16.59%) patients had a poor functional outcome. In multivariate logistic regression, patients in the highest tertile of baPWV (>22.25 m/s) were found to be at increased risk for poor functional outcome (adjusted odds ratio, 1.88; 95% confidence interval, 1.06-3.40) compared with those in the lowest tertile (<17.55 m/s). No significant interaction between baPWV and stroke subtype was noted. Receiver operating characteristic curve analysis indicated that the addition of baPWV to the prediction model significantly improved the discrimination ability for poor functional outcome. CONCLUSIONS - : baPWV has an independent prognostic value for predicting functional outcome after acute cerebral infarction. The prognostic value did not differ according to the stroke subtype.

Original languageEnglish
Pages (from-to)2305-2310
Number of pages6
JournalStroke
Volume45
Issue number8
DOIs
Publication statusPublished - 2014 Aug

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialised Nursing

Fingerprint Dive into the research topics of 'Brachial-ankle pulse wave velocity for predicting functional outcome in acute stroke'. Together they form a unique fingerprint.

  • Cite this

    Kim, J., Song, T. J., Kim, E. H., Lee, K. J., Lee, H. S., Nam, C. M., Song, D., Nam, H. S., Kim, Y. D., & Heo, J. H. (2014). Brachial-ankle pulse wave velocity for predicting functional outcome in acute stroke. Stroke, 45(8), 2305-2310. https://doi.org/10.1161/STROKEAHA.114.005576