Abstract
Fibroadenoma is a common benign breast lesion and its malignant transformation is rare. There have been several case reports and studies that retrospectively reviewed breast cancers that arose within fibroadenomas; however, none of these studies reported serial changes in radiologic features of the cancer, including findings from mammography and ultrasound (US). We report a case of breast cancer arising adjacent to an involuting fibro adenoma in a 39-year-old woman who was undergoing serial follow-up after her fibroadenoma was diagnosed. Seven years after her diagnosis, the lesion showed evidence of coarse calcifications, a typical sign of involution. Four years later, US revealed a newly developed hypoechoic lesion with irregular margins and peripherally located calcifications adjacent to the fibroadenoma. A core biopsy was performed, and histopathological examination resulted in a diagnosis of invasive ductal carcinoma. When new suspicious features are observed in a fibroadenoma, radiologists should raise the concern for breast cancer and proceed with diagnosis and treatment accordingly.
| Original language | English |
|---|---|
| Pages (from-to) | 291-295 |
| Number of pages | 5 |
| Journal | Journal of Breast Cancer |
| Volume | 18 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2015 Sep |
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All Science Journal Classification (ASJC) codes
- Oncology
- Cancer Research
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Breast cancer arising adjacent to an involuting fibroadenoma : Serial changes in radiologic features. / Park, Chae Jung; Kim, Eun Kyung; Woo, Ha Young; Moon, Hee Jung; Yoon, Jung Hyun; Kim, Min Jung.
In: Journal of Breast Cancer, Vol. 18, No. 3, 09.2015, p. 291-295.Research output: Contribution to journal › Article
TY - JOUR
T1 - Breast cancer arising adjacent to an involuting fibroadenoma
T2 - Serial changes in radiologic features
AU - Park, Chae Jung
AU - Kim, Eun Kyung
AU - Woo, Ha Young
AU - Moon, Hee Jung
AU - Yoon, Jung Hyun
AU - Kim, Min Jung
PY - 2015/9
Y1 - 2015/9
N2 - Fibroadenoma is a common benign breast lesion and its malignant transformation is rare. There have been several case reports and studies that retrospectively reviewed breast cancers that arose within fibroadenomas; however, none of these studies reported serial changes in radiologic features of the cancer, including findings from mammography and ultrasound (US). We report a case of breast cancer arising adjacent to an involuting fibro adenoma in a 39-year-old woman who was undergoing serial follow-up after her fibroadenoma was diagnosed. Seven years after her diagnosis, the lesion showed evidence of coarse calcifications, a typical sign of involution. Four years later, US revealed a newly developed hypoechoic lesion with irregular margins and peripherally located calcifications adjacent to the fibroadenoma. A core biopsy was performed, and histopathological examination resulted in a diagnosis of invasive ductal carcinoma. When new suspicious features are observed in a fibroadenoma, radiologists should raise the concern for breast cancer and proceed with diagnosis and treatment accordingly.
AB - Fibroadenoma is a common benign breast lesion and its malignant transformation is rare. There have been several case reports and studies that retrospectively reviewed breast cancers that arose within fibroadenomas; however, none of these studies reported serial changes in radiologic features of the cancer, including findings from mammography and ultrasound (US). We report a case of breast cancer arising adjacent to an involuting fibro adenoma in a 39-year-old woman who was undergoing serial follow-up after her fibroadenoma was diagnosed. Seven years after her diagnosis, the lesion showed evidence of coarse calcifications, a typical sign of involution. Four years later, US revealed a newly developed hypoechoic lesion with irregular margins and peripherally located calcifications adjacent to the fibroadenoma. A core biopsy was performed, and histopathological examination resulted in a diagnosis of invasive ductal carcinoma. When new suspicious features are observed in a fibroadenoma, radiologists should raise the concern for breast cancer and proceed with diagnosis and treatment accordingly.
UR - http://www.scopus.com/inward/record.url?scp=84948686978&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84948686978&partnerID=8YFLogxK
U2 - 10.4048/jbc.2015.18.3.291
DO - 10.4048/jbc.2015.18.3.291
M3 - Article
AN - SCOPUS:84948686978
VL - 18
SP - 291
EP - 295
JO - Journal of Breast Cancer
JF - Journal of Breast Cancer
SN - 1738-6756
IS - 3
ER -