Breast cancer arising adjacent to an involuting fibroadenoma: Serial changes in radiologic features

Chae Jung Park, Eun Kyung Kim, Ha Young Woo, Hee Jung Moon, Jung Hyun Yoon, Min Jung Kim

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Fibroadenoma is a common benign breast lesion and its malignant transformation is rare. There have been several case reports and studies that retrospectively reviewed breast cancers that arose within fibroadenomas; however, none of these studies reported serial changes in radiologic features of the cancer, including findings from mammography and ultrasound (US). We report a case of breast cancer arising adjacent to an involuting fibro adenoma in a 39-year-old woman who was undergoing serial follow-up after her fibroadenoma was diagnosed. Seven years after her diagnosis, the lesion showed evidence of coarse calcifications, a typical sign of involution. Four years later, US revealed a newly developed hypoechoic lesion with irregular margins and peripherally located calcifications adjacent to the fibroadenoma. A core biopsy was performed, and histopathological examination resulted in a diagnosis of invasive ductal carcinoma. When new suspicious features are observed in a fibroadenoma, radiologists should raise the concern for breast cancer and proceed with diagnosis and treatment accordingly.

Original languageEnglish
Pages (from-to)291-295
Number of pages5
JournalJournal of Breast Cancer
Volume18
Issue number3
DOIs
Publication statusPublished - 2015 Sep

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Fibroadenoma
Breast Neoplasms
Mammary Ultrasonography
Ductal Carcinoma
Adenoma
Breast
Biopsy
Neoplasms

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Park, Chae Jung ; Kim, Eun Kyung ; Woo, Ha Young ; Moon, Hee Jung ; Yoon, Jung Hyun ; Kim, Min Jung. / Breast cancer arising adjacent to an involuting fibroadenoma : Serial changes in radiologic features. In: Journal of Breast Cancer. 2015 ; Vol. 18, No. 3. pp. 291-295.
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abstract = "Fibroadenoma is a common benign breast lesion and its malignant transformation is rare. There have been several case reports and studies that retrospectively reviewed breast cancers that arose within fibroadenomas; however, none of these studies reported serial changes in radiologic features of the cancer, including findings from mammography and ultrasound (US). We report a case of breast cancer arising adjacent to an involuting fibro adenoma in a 39-year-old woman who was undergoing serial follow-up after her fibroadenoma was diagnosed. Seven years after her diagnosis, the lesion showed evidence of coarse calcifications, a typical sign of involution. Four years later, US revealed a newly developed hypoechoic lesion with irregular margins and peripherally located calcifications adjacent to the fibroadenoma. A core biopsy was performed, and histopathological examination resulted in a diagnosis of invasive ductal carcinoma. When new suspicious features are observed in a fibroadenoma, radiologists should raise the concern for breast cancer and proceed with diagnosis and treatment accordingly.",
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Breast cancer arising adjacent to an involuting fibroadenoma : Serial changes in radiologic features. / Park, Chae Jung; Kim, Eun Kyung; Woo, Ha Young; Moon, Hee Jung; Yoon, Jung Hyun; Kim, Min Jung.

In: Journal of Breast Cancer, Vol. 18, No. 3, 09.2015, p. 291-295.

Research output: Contribution to journalArticle

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