Calcium phosphate nano-composite with bone morphogenetic protein

M. Park, H. Kim, J. W. Lee, K. Y. Lee, H. M. Kim, S. H. Moon, H. M. Lee

Research output: Contribution to journalArticle

Abstract

Thick coatings of bone morphogenetic protein (BMP)-calcium phosphate nano-composite were prepared by a biomimetic process, in which substrates were immersed in modified simulated body fluid containing rh-BMP2 at room temperature and pressure. In vitro analyses showed that the calcium phosphate and BMP formed stable and uniform coating of composite on surface of substrate, and that the composite derive significant improvement in tissue formation, suggesting an osteoinductive bioactive surface.

Original languageEnglish
Pages (from-to)361-364
Number of pages4
JournalKey Engineering Materials
Volume330-332 I
Publication statusPublished - 2007 Jan 24

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All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

Cite this

Park, M., Kim, H., Lee, J. W., Lee, K. Y., Kim, H. M., Moon, S. H., & Lee, H. M. (2007). Calcium phosphate nano-composite with bone morphogenetic protein. Key Engineering Materials, 330-332 I, 361-364.