Cancer trapping on sticky microgels through enhanced free thiols

Junghwa Cha, Jin Kyoung Shim, Seok-Gu Kang, Pilnam Kim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We propose a new method to treat the invading glioblastoma (GBM) cells by trapping within sticky microgels. To trap the invading cells within the microgels, we formulate the microgels to modify the redox system at the cell surfaces, enhancing the free-thiol mediated cell adhesion. By reducing the disulfide bonds into free-thiols at the cell surfaces, we could make the cells being trapped within the sticky microgels.

Original languageEnglish
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PublisherChemical and Biological Microsystems Society
Pages571-572
Number of pages2
ISBN (Electronic)9780979806490
Publication statusPublished - 2016 Jan 1
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: 2016 Oct 92016 Oct 13

Publication series

Name20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

Other

Other20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
CountryIreland
CityDublin
Period16/10/916/10/13

Fingerprint

Cell adhesion
Oxidation-Reduction

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

Cite this

Cha, J., Shim, J. K., Kang, S-G., & Kim, P. (2016). Cancer trapping on sticky microgels through enhanced free thiols. In 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 (pp. 571-572). (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016). Chemical and Biological Microsystems Society.
Cha, Junghwa ; Shim, Jin Kyoung ; Kang, Seok-Gu ; Kim, Pilnam. / Cancer trapping on sticky microgels through enhanced free thiols. 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, 2016. pp. 571-572 (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).
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title = "Cancer trapping on sticky microgels through enhanced free thiols",
abstract = "We propose a new method to treat the invading glioblastoma (GBM) cells by trapping within sticky microgels. To trap the invading cells within the microgels, we formulate the microgels to modify the redox system at the cell surfaces, enhancing the free-thiol mediated cell adhesion. By reducing the disulfide bonds into free-thiols at the cell surfaces, we could make the cells being trapped within the sticky microgels.",
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language = "English",
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Cha, J, Shim, JK, Kang, S-G & Kim, P 2016, Cancer trapping on sticky microgels through enhanced free thiols. in 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016, Chemical and Biological Microsystems Society, pp. 571-572, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016, Dublin, Ireland, 16/10/9.

Cancer trapping on sticky microgels through enhanced free thiols. / Cha, Junghwa; Shim, Jin Kyoung; Kang, Seok-Gu; Kim, Pilnam.

20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, 2016. p. 571-572 (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

TY - GEN

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Cha J, Shim JK, Kang S-G, Kim P. Cancer trapping on sticky microgels through enhanced free thiols. In 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society. 2016. p. 571-572. (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).